PDF(Pubmed)
Abstract：
UNASSIGNED: The aim was to systematically review the association between depression and frailty in the elderly.
UNASSIGNED: Databases such as PubMed, Web of Science, Embase, and Scopus were searched for articles on the link between the risk of depression and frailty since the creation of the databases to September 1, 2023. A pair of investigators collaboratively conducted the screening, collected data, and evaluated the potential for bias in the included studies. R software was utilized for meta-synthesis.
UNASSIGNED: Eight cohort studies comprising 13 043 participants and 14 854 senior individuals with depression were included. The meta-analysis showed that there was a significant connection regarding frailty and the incidence of depression among the elderly (Risk Ratio [RR] = 3.26, 95% Confidence Interval [CI]: 1.68-6.32). Subgroup evaluations showed that there was no association between frailty and depression in the community-dwelling elderly (RR = 2.28, 95% CI: 0.644-8.102) and in the elderly patients with depression assessed by Center for Epidemiological Studies Depression Scale (CES-D) (RR = 5.82, 95% CI: 0.481-70.526).
UNASSIGNED: Frailty is correlated with the risk of depression in the elderly. Frailty is a contributing factor to depression in the elderly.
UNASSIGNED: Databases such as PubMed, Web of Science, Embase, and Scopus were searched for articles on the link between the risk of depression and frailty since the creation of the databases to September 1, 2023. A pair of investigators collaboratively conducted the screening, collected data, and evaluated the potential for bias in the included studies. R software was utilized for meta-synthesis.
UNASSIGNED: Eight cohort studies comprising 13 043 participants and 14 854 senior individuals with depression were included. The meta-analysis showed that there was a significant connection regarding frailty and the incidence of depression among the elderly (Risk Ratio [RR] = 3.26, 95% Confidence Interval [CI]: 1.68-6.32). Subgroup evaluations showed that there was no association between frailty and depression in the community-dwelling elderly (RR = 2.28, 95% CI: 0.644-8.102) and in the elderly patients with depression assessed by Center for Epidemiological Studies Depression Scale (CES-D) (RR = 5.82, 95% CI: 0.481-70.526).
UNASSIGNED: Frailty is correlated with the risk of depression in the elderly. Frailty is a contributing factor to depression in the elderly.
摘要：
■目的是系统地回顾老年人抑郁和虚弱之间的关系。
■数据库，例如PubMed，WebofScience,Embase,从数据库创建到2023年9月1日，搜索了Scopus关于抑郁风险与虚弱之间联系的文章。一对研究人员合作进行了筛查，收集的数据,并评估了纳入研究中的偏差可能性。利用R软件进行元合成。
■纳入了8项队列研究，包括13043名参与者和14854名抑郁症患者。荟萃分析显示，老年人的虚弱与抑郁症的发生率之间存在显着联系（风险比[RR]=3.26，95％置信区间[CI]：1.68-6.32）。亚组评估显示，社区居住的老年人（RR=2.28，95％CI：0.644-8.102）和通过流行病学研究中心抑郁量表（CES-D）评估的老年抑郁症患者（RR=5.82，95％CI：0.481-70.526）之间没有联系。
■虚弱与老年人患抑郁症的风险相关。虚弱是导致老年人抑郁的一个因素。
■数据库，例如PubMed，WebofScience,Embase,从数据库创建到2023年9月1日，搜索了Scopus关于抑郁风险与虚弱之间联系的文章。一对研究人员合作进行了筛查，收集的数据,并评估了纳入研究中的偏差可能性。利用R软件进行元合成。
■纳入了8项队列研究，包括13043名参与者和14854名抑郁症患者。荟萃分析显示，老年人的虚弱与抑郁症的发生率之间存在显着联系（风险比[RR]=3.26，95％置信区间[CI]：1.68-6.32）。亚组评估显示，社区居住的老年人（RR=2.28，95％CI：0.644-8.102）和通过流行病学研究中心抑郁量表（CES-D）评估的老年抑郁症患者（RR=5.82，95％CI：0.481-70.526）之间没有联系。
■虚弱与老年人患抑郁症的风险相关。虚弱是导致老年人抑郁的一个因素。
