PDF(Pubmed)
Abstract：
UNASSIGNED: To explore the association between malnutrition and risk of depression in the elderly.
UNASSIGNED: Relevant studies were searched in PubMed, Web of Science, the Cochrane Library, Scopus, and Embase from the establishment of the database to August 17, 2023. Two researchers independently screened the literature, extracted data, and evaluated the risk of bias in the included studies. Stata16.0 software was used for meta-analysis.
UNASSIGNED: A total of 8 observational studies were identified with 11 112 participants, of which 2771 elderly patients had depression. The meta-pooled results showed a significant correlation between nutritional status and depression risk (odds ratio (OR) = 2.03, 95% CI = (1.47, 2.81), P < 0.001). Subgroup analysis found that the malnutrition scores of different study types and the diagnostic methods of depression and malnutrition were correlated with the risk of depression.
UNASSIGNED: Malnutrition was associated with depression risk in the elderly. Further large-scale multicenter studies should be conducted to test and verify the results.
UNASSIGNED: Relevant studies were searched in PubMed, Web of Science, the Cochrane Library, Scopus, and Embase from the establishment of the database to August 17, 2023. Two researchers independently screened the literature, extracted data, and evaluated the risk of bias in the included studies. Stata16.0 software was used for meta-analysis.
UNASSIGNED: A total of 8 observational studies were identified with 11 112 participants, of which 2771 elderly patients had depression. The meta-pooled results showed a significant correlation between nutritional status and depression risk (odds ratio (OR) = 2.03, 95% CI = (1.47, 2.81), P < 0.001). Subgroup analysis found that the malnutrition scores of different study types and the diagnostic methods of depression and malnutrition were correlated with the risk of depression.
UNASSIGNED: Malnutrition was associated with depression risk in the elderly. Further large-scale multicenter studies should be conducted to test and verify the results.
摘要：
■探讨老年人营养不良与抑郁风险之间的关系。
■在PubMed中搜索了相关研究，WebofScience,Cochrane图书馆,Scopus,和Embase从数据库建立到2023年8月17日。两名研究人员独立筛选了文献，提取的数据，并评估纳入研究的偏倚风险。采用Stata16.0软件进行Meta分析。
■共确定了8项观察性研究，共有11112名参与者，其中2771名老年患者患有抑郁症。meta汇总结果显示，营养状况与抑郁风险之间存在显着相关性（优势比（OR）=2.03，95％CI=（1.47，2.81），P<0.001)。亚组分析发现,不同研究类型的营养不良评分以及抑郁症和营养不良的诊断方法与抑郁风险相关。
■营养不良与老年人的抑郁风险相关。应进行进一步的大规模多中心研究以测试和验证结果。
■在PubMed中搜索了相关研究，WebofScience,Cochrane图书馆,Scopus,和Embase从数据库建立到2023年8月17日。两名研究人员独立筛选了文献，提取的数据，并评估纳入研究的偏倚风险。采用Stata16.0软件进行Meta分析。
■共确定了8项观察性研究，共有11112名参与者，其中2771名老年患者患有抑郁症。meta汇总结果显示，营养状况与抑郁风险之间存在显着相关性（优势比（OR）=2.03，95％CI=（1.47，2.81），P<0.001)。亚组分析发现,不同研究类型的营养不良评分以及抑郁症和营养不良的诊断方法与抑郁风险相关。
■营养不良与老年人的抑郁风险相关。应进行进一步的大规模多中心研究以测试和验证结果。
