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Abstract：
UNASSIGNED: Bipolar disorder (BD) is a recurrent chronic disease. There are few Chinese studies to explore the BD after ischemic stroke. This study aimed to analyze the high risk factors of BD after ischemic stroke and investigate prevention strategies.
UNASSIGNED: 197 patients with ischemic stroke in our hospital from March 2020 to March 2022 were selected as research subjects. The demographic information, clinical data, and scores of Mood Disorder Questionnaire (MDQ) and Activity of Daily Living Scale (ADL) in patients were retrospectively analyzed to count the incidence of BD in patients. Binary logistic regression analysis was used to analyze the influencing factors for BD after ischemic stroke, and preventive measures were discussed based on study results.
UNASSIGNED: The incidence of BD in patients with ischemic stroke was 45.18% (89/197), and the median and quartile in the first part of MDQ score was 6.00 (5.00,10.00) points. The subjects were divided into BD group (n = 89) and non-BD group (n = 108) based on the presence of BD in patients with ischemic stroke. Education background (OR = 0.485), lesions involving the frontal or temporal lobes (OR = 2.724), sleep disorders (OR = 2.246), and daily living ability (OR = 3.108) were influencing factors for BD after ischemic stroke (P < .05).
UNASSIGNED: The risk of BD after ischemic stroke is high. Based on the above research results, clinical attention should be paid to knowledge popularization, lesion examination, and the improvement of sleep quality and daily living ability, to prevent the occurrence of BD and improve the prognosis.
UNASSIGNED: 197 patients with ischemic stroke in our hospital from March 2020 to March 2022 were selected as research subjects. The demographic information, clinical data, and scores of Mood Disorder Questionnaire (MDQ) and Activity of Daily Living Scale (ADL) in patients were retrospectively analyzed to count the incidence of BD in patients. Binary logistic regression analysis was used to analyze the influencing factors for BD after ischemic stroke, and preventive measures were discussed based on study results.
UNASSIGNED: The incidence of BD in patients with ischemic stroke was 45.18% (89/197), and the median and quartile in the first part of MDQ score was 6.00 (5.00,10.00) points. The subjects were divided into BD group (n = 89) and non-BD group (n = 108) based on the presence of BD in patients with ischemic stroke. Education background (OR = 0.485), lesions involving the frontal or temporal lobes (OR = 2.724), sleep disorders (OR = 2.246), and daily living ability (OR = 3.108) were influencing factors for BD after ischemic stroke (P < .05).
UNASSIGNED: The risk of BD after ischemic stroke is high. Based on the above research results, clinical attention should be paid to knowledge popularization, lesion examination, and the improvement of sleep quality and daily living ability, to prevent the occurrence of BD and improve the prognosis.
摘要：
■双相情感障碍（BD）是一种反复发作的慢性疾病。国内很少有研究探讨缺血性脑卒中后的BD。本研究旨在分析缺血性卒中后BD的高危因素并探讨预防策略。
■选择2020年3月至2022年3月我院收治的197例缺血性脑卒中患者作为研究对象。人口统计信息，临床资料,回顾性分析患者的情绪障碍问卷（MDQ）和日常生活活动能力量表（ADL）评分，统计患者BD的发生率。采用二元Logistic回归分析缺血性脑卒中后BD的影响因素,并根据研究结果探讨了预防措施。
■缺血性卒中患者BD的发生率为45.18%(89/197),MDQ评分第一部分的中位数和四分位数分别为6.00(5.00,10.00)分。根据缺血性卒中患者是否存在BD，将受试者分为BD组（n=89）和非BD组（n=108）。教育背景（OR=0.485），累及额叶或颞叶的病变（OR=2.724），睡眠障碍（OR=2.246），日常生活能力(OR=3.108)是缺血性脑卒中后BD的影响因素(P<0.05)。
■缺血性卒中后BD的风险很高。基于以上研究成果,临床应重视知识普及，病变检查,睡眠质量和日常生活能力的提高，预防BD的发生,改善预后。
■选择2020年3月至2022年3月我院收治的197例缺血性脑卒中患者作为研究对象。人口统计信息，临床资料,回顾性分析患者的情绪障碍问卷（MDQ）和日常生活活动能力量表（ADL）评分，统计患者BD的发生率。采用二元Logistic回归分析缺血性脑卒中后BD的影响因素,并根据研究结果探讨了预防措施。
■缺血性卒中患者BD的发生率为45.18%(89/197),MDQ评分第一部分的中位数和四分位数分别为6.00(5.00,10.00)分。根据缺血性卒中患者是否存在BD，将受试者分为BD组（n=89）和非BD组（n=108）。教育背景（OR=0.485），累及额叶或颞叶的病变（OR=2.724），睡眠障碍（OR=2.246），日常生活能力(OR=3.108)是缺血性脑卒中后BD的影响因素(P<0.05)。
■缺血性卒中后BD的风险很高。基于以上研究成果,临床应重视知识普及，病变检查,睡眠质量和日常生活能力的提高，预防BD的发生,改善预后。
