Abstract：
Polypharmacy in psychiatry is an in-depth examination of drug-drug interactions and treatment challenges that explores the intricate landscape of psychiatric polypharmacy, a practice involving the prescription of multiple medications to individuals with mental health disorders. This review is based on the critical aspects of drug-drug interactions and the associated treatment challenges. Psychiatric polypharmacy is motivated by the complexity of mental health conditions, where monotherapy may be insufficient. While it offers potential benefits, the practice raises concerns related to drug interactions that can compromise safety and efficacy. The review delves into the prevalence and clinical indications for psychiatric polypharmacy, thoroughly analyzing drug interactions, treatment challenges, and strategies for mitigation. Real-world case studies illustrate the complexities and outcomes of managing complex medication regimens, while emerging trends in personalized medicine, advancements in psychopharmacology, multidisciplinary approaches, and digital health solutions offer a glimpse into the future of psychiatric polypharmacy. This examination underscores the importance of a patient-centered, evidence-based approach in optimizing psychiatric polypharmacy to achieve therapeutic benefits while minimizing risks.
摘要：
精神病学中的多药是对药物-药物相互作用和治疗挑战的深入检查，探索了精神病学多药的复杂景观，一种涉及为精神健康障碍患者开具多种药物的做法。这篇综述基于药物-药物相互作用的关键方面和相关的治疗挑战。精神病学的多重用药是由心理健康状况的复杂性引起的，单一疗法可能不足。虽然它提供了潜在的好处，这种做法引起了与可能损害安全性和有效性的药物相互作用相关的担忧.该综述深入研究了精神病多重用药的患病率和临床适应症，彻底分析药物相互作用，治疗挑战,和缓解策略。实际案例研究说明了管理复杂药物治疗方案的复杂性和结果，虽然个性化医疗的新兴趋势，精神药理学的进步，多学科方法，和数字健康解决方案提供了对精神科多重用药的未来一瞥。这项检查强调了以病人为中心的重要性，基于证据的方法来优化精神病多重用药，以实现治疗益处，同时将风险降至最低。
