关键词: COVID-19 metabolism microbiota nutrition translational medicine vitamins

来  源:   DOI:10.2174/0118715303296892240506100532

Abstract:
The COVID-19 pandemic impacted all areas of daily life, including medical care. Unfortunately, to date, no specific treatments have been found for the cure of this disease, and therefore, it is advisable to implement all possible strategies to prevent infection. In this context, it is important to better define the role of all behaviors, in particular nutrition, in order to establish whether these can both prevent infection and improve the outcome of the disease in patients with COVID-19. There is sufficient evidence to demonstrate that immune response can be weakened by inadequate nutrition. Nutrition management and treatment are very important to enhance the immune response of an infected person against RNA viral infection. A complete nutritional assessment should include anthropometric, dietary, and laboratorial assessment, as well as a multidisciplinary discussion about the patient\'s clinical condition. In this way, it is possible to establish an individualized nutritional approach to contribute to improving clinical and nutritional prognoses. From this point of view, diet, through intake of vitamins and trace elements and maintaining adequate functioning of the intestinal barrier, can reduce the severity of the COVID-19 infection. In this study, we provide an overview of the effects of diet on COVID-19 infection in non-cancer patients. This notion needs to be further evaluated, and thus, identification, characterization, and targeting of the right nutrition principles related to the management of patients with COVID-19 are likely to improve outcomes and may prevent the infection or lead to a cure.
摘要:
COVID-19大流行影响了日常生活的各个领域,包括医疗。不幸的是,到目前为止,没有找到治愈这种疾病的特定治疗方法,因此,建议实施所有可能的策略来预防感染。在这种情况下,重要的是要更好地定义所有行为的作用,特别是营养,以确定这些是否既可以预防感染又可以改善COVID-19患者的疾病结局。有足够的证据表明,营养不足会削弱免疫反应。营养管理和治疗对于增强感染者对RNA病毒感染的免疫反应非常重要。完整的营养评估应包括人体测量学,饮食,和实验室评估,以及关于患者临床状况的多学科讨论。这样,有可能建立个性化的营养方法,有助于改善临床和营养预后。从这个角度来看,饮食,通过摄入维生素和微量元素并保持肠道屏障的充分功能,可以降低COVID-19感染的严重程度。在这项研究中,我们概述了饮食对非癌症患者COVID-19感染的影响.这个概念需要进一步评估,因此,identification,表征,以及与COVID-19患者管理相关的正确营养原则可能会改善预后,并可能预防感染或导致治愈。
公众号