Abstract：
A simple, low-cost, and highly sensitive method using a modified QuECHERS procedure based on a liquid chromatography-tandem mass spectrometer (LC-MS/MS) was established to simultaneously quantify lufenuron and chlorfenapyr and the corresponding metabolite tralopyril in cabbage for the first time. On the basis of this method, terminal residue and dietary risk of lufenuron and chlorfenapyr in cabbage were investigated. The recoveries of lufenuron, chlorfenapyr, and tralopyril ranged from 88 to 110%, with relative standard deviation of less than 12.4%. The field trial results showed that at the pre-harvest interval (PHI) of 21 days, the terminal residues of lufenuron, chlorfenapyr, and tralopyril in the supervised trials were not higher than 0.02 mg/kg, and the highest detected residue levels of lufenuron, chlorfenapyr, and tralopyril were 0.047, 0.055, and <0.02 mg·kg-1 at 14-day pre-harvest respectively, which were lower than the maximum residue limits (MRLs) for cabbage established in China. For the dietary risk assessment, the national estimated daily intakes (NEDIs) as proportion of acceptable daily intakes (ADIs) were 80.4% and 29.9% for chlorfenapyr and lufenuron respectively indicating an acceptable dietary risk to Chinese population.
摘要：
一个简单的，低成本,首次建立了基于液相色谱-串联质谱仪（LC-MS/MS）的改良QuECHERS程序的高灵敏度方法，以同时定量卷心菜中的氯芬草隆和氯非那霉素以及相应的代谢产物曲妥普利。在此方法的基础上,研究了卷心菜中氟芬隆和氯非那霉素的终末残留和饮食风险。卢芬隆的回收率，氯非那霉素,曲洛普利从88%到110%不等，相对标准偏差小于12.4%。田间试验结果表明，在21天的收获前间隔（PHI），卢芬隆的末端残基，氯非那霉素,和曲普利在监督试验中不高于0.02mg/kg，和检测到的最高残留水平的卢芬隆，氯非那霉素,收获前14天，曲洛普利分别为0.047、0.055和<0.02mg·kg-1，低于中国建立的白菜最大残留限值(MRL)。对于饮食风险评估，国家估计日摄入量(NEDIs)占可接受日摄入量(ADIs)的比例分别为80.4%和29.9%,表明中国人群的饮食风险可接受.
