PDF(Pubmed)
Abstract：
The present study investigated the prevalence of blood chloride (Cl) abnormalities in diarrheic neonatal calves with metabolic acidosis and attempted to identify the most relevant electrolyte abnormality to these abnormalities. A retrospective analysis was conducted on the medical records of 157 diarrheic neonatal calves aged 10.3 ± 4.2 days old with metabolic acidosis. Hypochloremia, normochloremia, and hyperchloremia were observed in 8.9% (14/157), 43.3% (68/157), and 47.8% (68/157), respectively, of diarrheic calves with metabolic acidosis. This distribution remained similar regardless of age (under 8 days or 8 days and older). Furthermore, a multiple logistic regression analysis showed that variations in values for blood sodium [Na (regression coefficients 0.877; 95% confidence interval (CI) 13.977-134.195; P<0.01)], pH (regression coefficients -10.719; 95% CI -19.076- -2.362; P<0.05), and bicarbonate [HCO3- (regression coefficients -0.555; 95% CI -0.820- -0.290; P<0.01)] were associated with blood Cl abnormalities. The present results revealed that blood Na concentrations were more strongly associated with blood Cl concentrations than blood pH and HCO3- values. In the present study, diarrheic calves with hyperchloremia were characterized by normonatremia and extremely severe metabolic acidosis.
摘要：
本研究调查了患有代谢性酸中毒的腹泻新生小牛血氯化物（Cl）异常的患病率，并试图确定与这些异常最相关的电解质异常。方法对157例10.3±4.2日龄腹泻型新生小牛代谢性酸中毒的病历资料进行回顾性分析。低氯血症,正常低血血症,观察到高氯血症为8.9％（14/157），43.3%（68/157），和47.8%(68/157)，分别,有代谢性酸中毒的腹泻小牛。无论年龄（8天以下或8天及以上），这种分布都保持相似。此外，多元逻辑回归分析显示血钠值的变化[Na（回归系数0.877;95％置信区间（CI）13.977-134.195；P<0.01）]，pH（回归系数-10.719；95%CI-19.076--2.362；P<0.05），和碳酸氢盐[HCO3-（回归系数-0.555;95％CI-0.820--0.290;P<0.01）]与血液Cl异常有关。本结果表明，与血液pH和HCO3-值相比，血液Na浓度与血液Cl浓度的相关性更强。在本研究中,高氯血症的腹泻小牛的特征是正常血症和极严重的代谢性酸中毒。
