Abstract：
OBJECTIVE: Comparison of naturally conceived pregnancy with IVFET pregnancy for feto-maternal outcome and morphology and histopathology of placenta & umbilical cord.
METHODS: 100 pregnant women were divided into 2 subsets of spontaneous pregnancy group (n = 50) and the IVFET pregnancy group (n = 50).The two groups were compared for Maternal age, parity, maternal weight gain, prepregnancy maternal BMI, gestational age, birth weight of baby, placental weight, placenta and umbilical cord cross sections, insertion site of the umbilical cord, and length of the umbilical cord.
METHODS: Patients registered at ANC OPD/ART centre of our institute and subsequently reporting to maternity ward/ labor room for delivery at our centre.
METHODS: The pregnancies conceived after ART outside our institute, multifetal pregnancies. Study duration: 01 year Results: Our study revealed that spontaneous pregnancy group had less antenatal co-morbidities with more number of term vaginal deliveries and less intrapartum and neonatal complications compared to IVFET pregnancy women (p < 0.05).
CONCLUSIONS: Assisted reproductive technologies have an impact on placental growth and function in pregnancy. The occurrence of placental abnormalities were the most significant and pertinent finding in the IVF-ET placentas. On histopathological examination maternal vascular malperfusion and concomitant anomalies of the umbilical cord were most noticeable findings.
METHODS: 100 pregnant women were divided into 2 subsets of spontaneous pregnancy group (n = 50) and the IVFET pregnancy group (n = 50).The two groups were compared for Maternal age, parity, maternal weight gain, prepregnancy maternal BMI, gestational age, birth weight of baby, placental weight, placenta and umbilical cord cross sections, insertion site of the umbilical cord, and length of the umbilical cord.
METHODS: Patients registered at ANC OPD/ART centre of our institute and subsequently reporting to maternity ward/ labor room for delivery at our centre.
METHODS: The pregnancies conceived after ART outside our institute, multifetal pregnancies. Study duration: 01 year Results: Our study revealed that spontaneous pregnancy group had less antenatal co-morbidities with more number of term vaginal deliveries and less intrapartum and neonatal complications compared to IVFET pregnancy women (p < 0.05).
CONCLUSIONS: Assisted reproductive technologies have an impact on placental growth and function in pregnancy. The occurrence of placental abnormalities were the most significant and pertinent finding in the IVF-ET placentas. On histopathological examination maternal vascular malperfusion and concomitant anomalies of the umbilical cord were most noticeable findings.
摘要：
目的：比较自然妊娠与IVFET妊娠对胎儿-母体结局以及胎盘和脐带形态和组织病理学的影响。
方法：将100例孕妇分为自然妊娠组（n=50）和IVFET妊娠组（n=50）。比较两组产妇年龄,奇偶校验，母体体重增加,孕前孕妇BMI,胎龄,婴儿出生体重,胎盘重量,胎盘和脐带横截面，脐带的插入部位，和脐带的长度。
方法：患者在我们研究所的ANCOPD/ART中心注册，随后报告到我们中心的产房/分娩室。
方法：我们研究所外的ART后怀孕，多胎妊娠.研究持续时间：01年结果：我们的研究表明，与IVFET妊娠妇女相比，自然妊娠组产前合并症较少，足月阴道分娩次数较多，产时和新生儿并发症较少（p<0.05）。
结论：辅助生殖技术对妊娠胎盘生长和功能有影响。胎盘异常的发生是IVF-ET胎盘中最重要和最相关的发现。在组织病理学检查中，母体血管灌注不良和伴随的脐带异常是最明显的发现。
方法：将100例孕妇分为自然妊娠组（n=50）和IVFET妊娠组（n=50）。比较两组产妇年龄,奇偶校验，母体体重增加,孕前孕妇BMI,胎龄,婴儿出生体重,胎盘重量,胎盘和脐带横截面，脐带的插入部位，和脐带的长度。
方法：患者在我们研究所的ANCOPD/ART中心注册，随后报告到我们中心的产房/分娩室。
方法：我们研究所外的ART后怀孕，多胎妊娠.研究持续时间：01年结果：我们的研究表明，与IVFET妊娠妇女相比，自然妊娠组产前合并症较少，足月阴道分娩次数较多，产时和新生儿并发症较少（p<0.05）。
结论：辅助生殖技术对妊娠胎盘生长和功能有影响。胎盘异常的发生是IVF-ET胎盘中最重要和最相关的发现。在组织病理学检查中，母体血管灌注不良和伴随的脐带异常是最明显的发现。
