Abstract：
Avascular necrosis (AVN) is linked to considerable morbidity, resulting in severe pain and functional impairment. Herein, for the first time, we reported an 18-year-old patient with Crohn\'s disease during the remission phase under Azathioprine therapy who presented with articular pain. Although no underlying risk factors, the patient was diagnosed with severe AVN of the bilateral femoral head and both knees simultaneously following pain in involved areas. This case highlights the importance of demand multidisciplinary approach to chronic disease. Moreover, clinicians should be aware of articular manifestations in IBD patients to diagnose and treat these conditions as soon as possible. Patients should be evaluated for their psychologic, gastrointestinal, and extra-gastrointestinal comorbidities during each follow-up visit.
摘要：
无血管坏死(AVN)与相当高的发病率有关，导致严重的疼痛和功能障碍。在这里，第一次,我们报道了一名18岁的克罗恩病患者,在硫唑嘌呤治疗缓解期,出现关节疼痛.虽然没有潜在的风险因素，患者在受累区域疼痛后被诊断为双侧股骨头和双膝同时严重AVN.这个案例强调了需求多学科方法对慢性病的重要性。此外，临床医生应了解IBD患者的关节表现，以尽快诊断和治疗这些疾病。应该对患者进行心理评估，胃肠,以及每次随访期间的胃肠道外合并症。
