Abstract：
Oral psoriasis therapies include both older traditional immunosuppressants, such as methotrexate, cyclosporine, and acitretin, as well as newer, more targeted agents, such as apremilast, deucravacitinib, and oral interleukin-23 receptor antagonists. Patients may prefer oral therapies to injectable therapies based on the route of administration. Both older and newer oral psoriasis therapies can be utilized effectively in the treatment of psoriasis. Here, we will review oral agents used in the treatment of psoriasis as well as provide commentary on their role in our current, evolving psoriasis treatment paradigm.
摘要：
口服牛皮癣疗法包括较老的传统免疫抑制剂，比如甲氨蝶呤,环孢菌素,和阿西汀,以及较新的，更有针对性的特工，比如apremilast，deucravitinib,和口服白介素-23受体拮抗剂。基于给药途径,患者可能更喜欢口服疗法而不是可注射疗法。较旧和较新的口服牛皮癣疗法都可以有效地用于牛皮癣的治疗。这里,我们将回顾用于治疗牛皮癣的口服药物，并就它们在我们目前的作用提供评论，不断发展的牛皮癣治疗范式。
