关键词: Abortion Cattle Malformations Phytometabolites Reproduction

Mesh : Animals Ruminants Reproduction / drug effects Alkaloids Plants, Toxic / toxicity Female Plant Poisoning / veterinary

来  源:   DOI:10.1016/j.toxicon.2024.107769

Abstract:
The presence of phytotoxins in plants constitutes a health risk for herbivores, particularly on ruminants who accidently consume them. Among the adverse effects produced by these are reproductive alterations, represented by abortion, infertility, and morphological alterations in neonates, which are frequently attributed to other causes. While in some cases the plants that contain such metabolites are known, other times they are not, leading to alterations that are difficult to treat considering that their toxicodynamics are unknown. The objective of this documentary research is to provide information on how metabolites such as phytoestrogens, L-mimosine, labdane diterpenoids - isocupressic acid, quinolizidine alkaloids and piperidine swainsonine, anabasine, coniine and associated alkaloids, among others, exert their action in the animal organism and the effects they produce.
摘要:
植物中植物毒素的存在对草食动物构成了健康风险,特别是那些意外食用它们的反刍动物。这些产生的不利影响包括生殖改变,以堕胎为代表,不孕症,和新生儿的形态学改变,这通常归因于其他原因。虽然在某些情况下,含有这种代谢物的植物是已知的,其他时候他们不是,考虑到它们的毒性动力学未知,导致难以治疗的改变。这项文献研究的目的是提供有关植物雌激素等代谢物的信息,L-含羞草苷,labdane二萜-异芥酸,喹啉嗪生物碱和哌啶苦豆素,anabasine,coniine和相关生物碱,其中,在动物有机体及其产生的影响中发挥它们的作用。
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