Abstract：
Since the scrotum is rarely exposed to sunlight, basal cell carcinoma (BCC) development in this area is an uncommon occurrence. As result, there is a scarcity of research covering this particular presentation, which poses a diagnostic and therapeutic challenge for clinicians. The objective of this systematic review is to provide a thorough overview of scrotal BCC, including a summary of its clinical characteristics, and microscopic subtypes. It also seeks to discuss the many techniques used in the management of this uncommon clinical presentation. Utilizing data from 1957 to October 2023, a systematic review of PubMed and Wiley Online Library was conducted to identify all cases of scrotal BCC with various presentations and managements. A total of 73 patients were included. The median patient age was 65.9 years (range 42 to 87). All studies were either case reports or case series. Our review shows that treatment with Mohs micrographic surgery (MMS), leads to a superior patient outcome based on anecdotal evidence in select cases. To deepen our understanding of Mohs surgery\'s efficacy in treating scrotal BCC, it is imperative to conduct more robust research in the form of randomized clinical trials.
摘要：
由于阴囊很少暴露在阳光下，基底细胞癌（BCC）在该区域的发展并不常见。因此,缺乏涵盖这一特定演示的研究，这对临床医生提出了诊断和治疗挑战。本系统综述的目的是提供对阴囊BCC的全面概述，包括其临床特征的总结，和微观亚型。它还试图讨论在这种罕见的临床表现的管理中使用的许多技术。利用1957年至2023年10月的数据，对PubMed和Wiley在线图书馆进行了系统审查，以通过各种演示和管理来识别所有阴囊BCC病例。共纳入73例患者。患者年龄中位数为65.9岁（范围为42至87岁）。所有研究均为病例报告或病例系列。我们的评论显示，用Mohs显微手术(MMS)治疗，在选定的病例中，根据轶事证据，导致更好的患者预后。为了加深我们对Mohs手术治疗阴囊BCC疗效的理解，必须以随机临床试验的形式进行更有力的研究。
