PDF(Pubmed)
Abstract：
Digital weight loss interventions present a viable and cost-effective alternative to traditional therapy. However, further evidence is needed to establish the equal effectiveness of both approaches. This randomized controlled non-inferiority trial aimed to compare the effects of an intensive in-person weight loss intervention program with Vitadio digital therapy. One hundred patients with obesity and diagnosed with type 2 diabetes, prediabetes, or insulin resistance were enrolled and randomly assigned to one of the two treatment groups. Over a 6-month period, the control group received five in-person consultations with a physician who specialized in obesity treatment, a dietitian and/or a nutrition nurse, while the intervention group followed the digital program based on a multimodal therapeutic approach. The extent of weight loss was assessed and compared between the groups. Additionally, changes in body composition and metabolic parameters for the digital intervention group were analyzed. The study results demonstrated comparable effectiveness of both treatments for weight reduction. The positive effects of Vitadio were further evidenced by favorable changes in body composition and lipid metabolism and improved glycemic control in the intervention group. These findings suggest that Vitadio is an effective tool for assisting patients with managing obesity and preventing diabetes progression.
摘要：
数字减肥干预为传统治疗提供了可行且具有成本效益的替代方案。然而,需要进一步的证据来确定两种方法的同等有效性。这项随机对照非劣效性试验旨在比较强化的当面减肥干预计划与Vitadio数字治疗的效果。100名肥胖并被诊断为2型糖尿病的患者，前驱糖尿病，纳入或胰岛素抵抗,并随机分配到两个治疗组之一.在6个月的时间里,对照组接受了五次专门治疗肥胖的医生的面对面咨询，营养师和/或营养护士，而干预组遵循基于多模式治疗方法的数字程序。评估并比较各组之间的体重减轻程度。此外,分析了数字干预组的身体成分和代谢参数的变化。研究结果表明，两种治疗方法对减轻体重的有效性相当。Vitadio的积极作用进一步通过干预组的身体成分和脂质代谢的有利变化以及改善的血糖控制得到证明。这些发现表明，Vitadio是帮助患者控制肥胖和预防糖尿病进展的有效工具。
