PDF(Pubmed)
Abstract：
This article reports the results of an ecological study of cancer incidence rates by state in the US for the period 2016-2020. The goals of this study were to determine the extent to which solar UVB doses reduced cancer risk compared to findings reported in 2006 for cancer mortality rates for the periods 1950-1969 and 1970-1794 as well as cancer incidence rates for the period 1998-2002 and to determine which factors were recently associated with cancer risk. The cancer data for non-Hispanic white (European American) men and women were obtained from the Centers for Disease Control and Prevention. Indices were obtained for solar UVB at the surface for July 1992, and alcohol consumption, diabetes, and obesity prevalence near the 2016-2020 period. Lung cancer incidence rates were also used in the analyses as a surrogate for smoking, diet, and air pollution. The cancers for which solar UVB is significantly associated with reduced incidence are bladder, brain (males), breast, corpus uteri, esophageal, gastric, non-Hodgkin\'s lymphoma, pancreatic, and renal cancer. Lung cancer was significantly associated with colorectal, laryngeal, and renal cancer. Diabetes was also significantly associated with breast, liver, and lung cancer. Obesity prevalence was significantly associated with breast, colorectal, and renal cancer. Alcohol consumption was associated with bladder and esophageal cancer. Thus, diet has become a very important driver of cancer incidence rates. The role of solar UVB in reducing the risk of cancer has been reduced due to people spending less time outdoors, wearing sunscreen that blocks UVB but not UVA radiation, and population increases in terms of overweight and obese individuals, which are associated with lower 25-hydroxyvitamin D concentrations and the generation of systemic inflammation, which is a risk factor for cancer. A dietary approach that would reduce the risk of diabetes, obesity, lung cancer, and, therefore, cancer, would be one based mostly on whole plants and restrictions on red and processed meats and ultraprocessed foods. Solar UVB exposure for a few minutes before applying sunscreen and taking vitamin D supplements would also help reduce the risk of cancer.
摘要：
本文报告了2016-2020年美国各州癌症发病率的生态学研究结果。这项研究的目标是确定与2006年报告的1950-1969年和1970-1794年期间的癌症死亡率以及1998-1998年期间的癌症发病率相比，太阳能UVB剂量降低癌症风险的程度2002，并确定哪些因素最近与癌症风险相关。非西班牙裔白人（欧洲裔美国人）男性和女性的癌症数据来自疾病控制和预防中心。获得了1992年7月地表的太阳UVB指数，以及酒精消费，糖尿病,和肥胖患病率接近2016-2020年。肺癌发病率也在分析中用作吸烟的替代品，饮食，和空气污染。太阳能UVB与发病率降低显著相关的癌症是膀胱癌，大脑（男性），乳房,子宫体,食道,胃,非霍奇金淋巴瘤,胰腺,和肾癌。肺癌与结直肠癌显著相关，喉,和肾癌。糖尿病也与乳腺显著相关，肝脏,还有肺癌.肥胖患病率与乳房显着相关，结直肠,和肾癌。饮酒与膀胱癌和食管癌有关。因此，饮食已经成为癌症发病率的一个非常重要的驱动因素。由于人们在户外花费的时间减少，太阳能UVB在降低癌症风险方面的作用已经降低，穿着防晒霜可以阻止UVB但不阻止UVA辐射，超重和肥胖人群的人口增加，这与较低的25-羟基维生素D浓度和全身性炎症的产生有关，这是癌症的危险因素。一种能降低患糖尿病风险的饮食方法，肥胖，肺癌,and,因此,癌症,将主要基于整株植物，并限制红肉和加工肉类以及超加工食品。在使用防晒霜和服用维生素D补充剂之前，暴露于太阳能UVB几分钟也有助于降低患癌症的风险。
