PDF(Pubmed)
Abstract：
Duck Tembusu Virus (DTMUV) is a pathogen of the Flaviviridae family that causes infections in poultry, leading to significant economic losses in the duck farming industry in recent years. Ducks infected with this virus exhibit clinical symptoms such as decreased egg production and neurological disorders, along with serious consequences such as ovarian hemorrhage, organ enlargement, and necrosis. Variations in morbidity and mortality rates exist across different age groups of ducks. It is worth noting that DTMUV is not limited to ducks alone; it can also spread to other poultry such as chickens and geese, and antibodies related to DTMUV have even been found in duck farm workers, suggesting a potential risk of zoonotic transmission. This article provides a detailed overview of DTMUV research, delving into its genomic characteristics, vaccines, and the interplay with host immune responses. These in-depth research findings contribute to a more comprehensive understanding of the virus\'s transmission mechanism and pathogenic process, offering crucial scientific support for epidemic prevention and control.
摘要：
鸭坦布苏病毒（DTMUV）是黄病毒科的病原体，可导致家禽感染，导致近年来养鸭业的重大经济损失。感染这种病毒的鸭子表现出临床症状，如产蛋减少和神经系统疾病，伴随着严重的后果如卵巢出血,器官增大,和坏死。不同年龄段鸭子的发病率和死亡率存在差异。值得注意的是,DTMUV不仅限于鸭子;它还可以传播到其他家禽,如鸡和鹅,甚至在养鸭场工人中也发现了与DTMUV相关的抗体，提示人畜共患传播的潜在风险。本文提供了DTMUV研究的详细概述，深入研究其基因组特征，疫苗,以及与宿主免疫反应的相互作用。这些深入的研究成果有助于更全面地了解病毒的传播机制和致病过程,为疫情防控提供至关重要的科学支持。
