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Abstract：
A perfluoropolyether (PFPE)-based microfluidic device with cross-junction microchannels was fabricated with the purpose of producing uniform droplets. The microchannels were developed using CO2 laser engraving. PFPE was chosen as the main material because of its excellent solvent resistance. Polyethylene glycol diacrylate (PEGDA) was mixed with PFPE to improve the hydrophilic properties of the inner surface of the microchannels. The microchannels of the polydimethylsiloxane microfluidic device had a blackened and rough surface after laser engraving. By contrast, the inner surface of the microchannels of the PFPE-PEGDA microfluidic device exhibited a smooth surface. The lower power and faster speed of the laser engraving resulted in the development of microchannels with smaller dimensions, less than 30 μm in depth. The PFPE and PFPE-PEGDA microfluidic devices were used to produce uniform water and oil droplets, respectively. We believe that such a PFPE-based microfluidic device with CO2-laser-engraved microchannels can be used as a microfluidic platform for applications in various fields, such as biological and chemical analysis, extraction, and synthesis.
摘要：
制造具有交叉连接微通道的基于全氟聚醚(PFPE)的微流体装置,目的是产生均匀的液滴。使用CO2激光雕刻开发了微通道。PFPE因其优异的耐溶剂性被选择为主要材料。将聚乙二醇二丙烯酸酯(PEGDA)与PFPE混合以改善微通道内表面的亲水性。聚二甲基硅氧烷微流体装置的微通道在激光雕刻后具有变黑和粗糙的表面。相比之下,PFPE-PEGDA微流体装置的微通道的内表面表现出光滑的表面。激光雕刻的较低功率和较快速度导致了尺寸较小的微通道的发展，深度小于30μm。PFPE和PFPE-PEGDA微流控装置用于产生均匀的水滴和油滴，分别。我们认为，这种带有CO2激光雕刻微通道的基于PFPE的微流体设备可以用作在各个领域应用的微流体平台，如生物和化学分析，提取,和合成。
