PDF(Pubmed)
Abstract：
Background and Objectives: Assess the quality of life of children aged 2-10 with mild to moderate bronchial asthma. To evaluate the general health condition of children with mild and moderate severity bronchial asthma. To determine health changes in children with mild- and moderate-severity bronchial asthma as they grow older. To evaluate the impact of mild- and moderate-severity bronchial asthma on children\'s daily and social activities, physical health, emotional state, and general well-being. Materials and Methods: A comparative cross-sectional study was conducted in March-June 2020. Parents or guardians of 2-10-year-old children without bronchial asthma and children with mild to moderate bronchial asthma were interviewed after receiving their written informed consent. The questionnaire was based on the standardized quality-of-life quiz SF-36. A total of 248 questionnaires were collected-106 from the parents or guardians of children with bronchial asthma and 142 from parents/guardians of children without bronchial asthma. For further analysis, 106 children without bronchial asthma and with no chronic conditions were selected. Quantitative variables were compared using the Mann-Whitney U test and qualitative data using the chi-square (χ2) criteria. Quantitative data were described by giving means, medians, and standard deviations (SD); qualitative features by giving relative frequencies. Statistical data were analyzed using SPSS and Excel 2020. Results: Children with mild and moderate asthma exhibit poorer health compared to their healthy counterparts. Only 20.7% of respondents with asthma reported excellent or very good health, contrasting with 64.1% of healthy children (p < 0.001). As children with asthma age, their general condition improves, with 46.2% showing improvement in the past year, while 42.5% of healthy children had a stable condition (p < 0.05). In various activities, children with asthma face more constraints than healthy children (p < 0.05), including energetic activities (sick-59.5%; healthy-10.3%), moderate activities (sick-24.5%; healthy-4.7%), climbing stairs (sick-22.7%; healthy-3.8%), and walking over 100 m (sick-9.4%; healthy-0%). Children with asthma are more likely to experience exhaustion, anxiety, tiredness, lack of energy, and restraint in public activities (p < 0.05). Conclusions: Parents/caregivers of children with mild to moderate bronchial asthma rate their health worse than those of healthy children do. As children with mild to moderate bronchial asthma grow, the disease impact on their overall well-being decreases. Children with mild to moderate bronchial asthma, compared to healthy children, experience more limitations in vigorous or moderate activities; face more difficulties climbing stairs or walking more than 100 m; frequently feel exhaustion, anxiety, fatigue, or lack of energy; and encounter restrictions in social activities.
摘要：
背景和目的：评估2-10岁轻中度支气管哮喘患儿的生活质量。评价轻中度支气管哮喘患儿的一般健康状况。确定轻度和中度支气管哮喘儿童随着年龄增长的健康变化。评估轻度和中度支气管哮喘对儿童日常和社会活动的影响,身体健康,情绪状态,和总体福祉。材料与方法：2020年3月至6月进行了比较横断面研究。2-10岁无支气管哮喘儿童和轻度至中度支气管哮喘儿童的父母或监护人在获得书面知情同意书后进行了访谈。问卷基于标准的生活质量测验SF-36。共收集了248份问卷-106份来自支气管哮喘儿童的父母或监护人，142份来自无支气管哮喘儿童的父母/监护人。为了进一步分析，选择了106名无支气管哮喘且无慢性疾病的儿童。使用Mann-WhitneyU检验比较定量变量，并使用卡方（χ2）标准比较定性数据。定量数据通过给出的方法来描述，中位数，和标准偏差(SD)；通过给出相对频率的定性特征。使用SPSS和Excel2020对统计数据进行分析。结果：轻度和中度哮喘儿童与健康儿童相比，健康状况较差。只有20.7％的哮喘受访者表示健康状况良好或非常好。与健康儿童的64.1%(p<0.001)形成鲜明对比。随着哮喘儿童的年龄，他们的总体状况有所改善，46.2%在过去一年有所改善，而42.5%的健康儿童病情稳定(p<0.05)。在各种活动中,哮喘儿童比健康儿童面临更多的制约因素(p<0.05)，包括精力充沛的活动（生病-59.5%；健康-10.3%），适度活动（生病-24.5%；健康-4.7%），爬楼梯（生病-22.7%；健康-3.8%），行走超过100米（生病-9.4%；健康-0%）。患有哮喘的儿童更容易感到疲惫，焦虑,疲倦,缺乏能量,和限制公共活动(p<0.05)。结论：轻度至中度支气管哮喘儿童的父母/照顾者认为他们的健康状况比健康儿童差。随着轻度至中度支气管哮喘患儿的成长，疾病对他们整体幸福感的影响降低。儿童轻度至中度支气管哮喘，与健康儿童相比，在剧烈或适度的活动中经历更多的限制；面临更多的爬楼梯或行走超过100米的困难；经常感到疲惫，焦虑,疲劳,或缺乏能量；在社交活动中遇到限制。
