PDF(Pubmed)
Abstract：
(1) Background: the erythrocyte sedimentation rate (ESR) has been reported to increase in some infectious or inflammatory diseases in dogs, but no information on the frequency of increases in a routine clinical setting exists. The aim of this study was to assess the frequency of an increased ESR in dogs and to investigate its possible association with hematologic changes; (2) Methods: A total of 295 EDTA blood samples were randomly selected from the routine caseload of the Veterinary Teaching Hospital. Samples were grouped in controls and in pathologic groups based on the clinical presentation. A routine hemogram was performed, then the ESR was measured using the instrument MINI-PET; (3) Results: compared with controls, the ESR was significantly higher in all the pathologic groups, except for the hematological disorders group. The highest ESR was found in samples from dogs with chronic kidney disease or inflammation, followed by those from dogs with mild chronic disorders, severe/acute diseases, tumors and urinary disorders. The ESR negatively correlated with hematocrit and positively with neutrophil counts. (4) Conclusions: The ESR increases more frequently in dogs with clinically evident inflammation or CKD, but also in several other conditions, likely as a consequence of anemia and acute phase response.
摘要：
(1)背景:据报道,在狗的一些感染性或炎症性疾病中,红细胞沉降率(ESR)增加,但是没有关于常规临床环境中增加频率的信息。这项研究的目的是评估狗的ESR增加的频率，并研究其与血液学变化的可能关联；（2）方法：从兽医教学医院的常规病例中随机选择总共295份EDTA血样。根据临床表现将样品分为对照组和病理组。进行了常规血象检查，然后使用MINI-PET仪器测量ESR；（3）结果：与对照组相比，ESR在所有病理组中均显着较高，除了血液病组。在患有慢性肾脏疾病或炎症的狗的样本中发现最高的ESR，其次是患有轻度慢性疾病的狗，严重/急性疾病，肿瘤和泌尿系统疾病。ESR与血细胞比容呈负相关，与中性粒细胞计数呈正相关。(4)结论:临床上有明显炎症或CKD的犬ESR增加更频繁,但在其他几个条件下，可能是贫血和急性期反应的结果。
