PDF(Pubmed)
Abstract：
Non-healing claw horn disorders are a serious problem in dairy herds because of the long duration of the disorder and the chronic pain derived from it, seriously affecting animal welfare and causing decreased production and premature culling from the herd. In a clinical trial, 40 cows in 13 herds (12 dairy herds and 1 herd with cow-calf operations) with toe necrosis (TN, 27x) or a non-healing white line disorder (NHWLD, 13x) were treated topically with an unguent-containing zinc sulphate and acetyl acid in combination with a parenteral injection of tilmycosin. An evaluation was conducted 3 months after treatment using locomotion scoring (LS), a clinical observation of the lesion, and the lactation value (the lactation value is the Net Profit of the individual animal divided by the average Net Profit of the entire herd. The mean is 100, so >100 is related to better production (combination of kg milk, %fat, and protein)) (LV) before and after treatment. The mean LS improved significantly from 4.0 (SD: 0.2) before treatment to 1.2 (SD: 0.4) 3 months after treatment (p < 0.001). The clinical presentation showed that all of the cows were cured from horn shoe infection (both TN and NHWLD). The LVs of the treated cows increased significantly from 111.2 (SD: 12.2) to 116.8 (SD: 15.1; p = 0.003).
摘要：
由于该疾病的持续时间长以及由此引起的慢性疼痛，因此无法治愈的爪角疾病在奶牛群中是一个严重的问题，严重影响动物福利，导致产量下降和羊群过早扑杀。在临床试验中,13个牛群中的40头牛(12个牛群和1个牛牛手术)脚趾坏死(TN，27x）或不愈合的白线障碍（NHWLD，13x）用含药膏的硫酸锌和乙酰基酸局部治疗，并结合肠胃外注射tilmycosin。治疗后3个月使用运动评分（LS）进行评估，病变的临床观察，和泌乳值（泌乳值是个体动物的净利润除以整个畜群的平均净利润。平均值为100，因此>100与更好的产量有关(千克牛奶的组合，%脂肪，和蛋白质））（LV）治疗前后。平均LS从治疗前的4.0（SD：0.2）到治疗后3个月的1.2（SD：0.4）显着改善（p<0.001）。临床表现表明，所有母牛都从角鞋感染（TN和NHWLD）中治愈。处理母牛的LV从111.2(SD:12.2)显著增加至116.8(SD:15.1;p=0.003)。
