PDF(Pubmed)
Abstract：
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that disrupts brain functioning and is characterized by hyperactivity, impulsivity, and inattention. With varying presentations and complex etiological factors contributing to the development of ADHD, along with its persistence into adulthood, ADHD must be studied. Researchers have taken an interest in the relationship between ADHD and suicide, which is a serious public health concern with increasing prevalence rates in the Americas. The current literature reveals conflicting views on the importance of psychiatric comorbidities in the development of suicidal behaviours in ADHD patients. Therefore, this study aimed to determine whether there were significant differences between adult ADHD patients with suicide risk and adult ADHD patients without suicide risk. This study was a naturalistic retrospective chart review pilot study that used a sample of adults with a confirmed diagnosis of ADHD from January 2023 to August 2023. Using convenience sampling and sets of inclusion and exclusion criteria, patient data were sequentially collected from Med Access electronic medical records. The control and experimental groups each consisted of 50 patients (100) ranging from 19 to 58 years old. Our quantitative data were analyzed using non-parametric statistical tests, including the Chi-Square test and the Mann-Whitney U test. The results showed significant associations between ADHD patients with suicide risk and (1) borderline personality disorder; (2) binge eating disorder; (3) seven specific psychosocial risk factors; and (4) a higher number of antidepressant medication trials. No significant associations were found with other psychiatric disorders; however, there are important sex differences in terms of the risk factors. Our pilot study reveals several significant differences between adult ADHD patients with suicide risk and those without suicide risk. However, given our limited sample size and limitations, we hope our study encourages larger-scale studies to further investigate this relationship to improve its generalizability.
摘要：
注意缺陷多动障碍（ADHD）是一种常见的神经发育障碍，会破坏大脑功能，以多动症为特征，冲动,和注意力不集中。由于不同的表现和复杂的病因因素导致多动症的发展，随着它持续到成年，必须研究ADHD。研究人员对多动症和自杀之间的关系感兴趣，这是一个严重的公共卫生问题，在美洲患病率上升。目前的文献揭示了关于精神合并症在ADHD患者自杀行为发展中的重要性的相互矛盾的观点。因此,本研究旨在确定有自杀风险的成年ADHD患者与无自杀风险的成年ADHD患者之间是否存在显著差异.这项研究是一项自然主义的回顾性图表审查试点研究，使用了2023年1月至2023年8月确诊为ADHD的成年人样本。使用便利抽样和纳入和排除标准集，我们从MedAccess电子病历中依次收集患者数据.对照组和实验组各包括50名患者（100名），年龄从19岁到58岁。我们的定量数据采用非参数统计检验进行分析，包括卡方检验和曼-惠特尼U检验。结果显示，患有自杀风险的ADHD患者与（1）边缘性人格障碍之间存在显着关联；（2）暴饮暴食症；（3）七个特定的社会心理风险因素；（4）抗抑郁药物试验的数量更高。没有发现与其他精神疾病的显著关联；然而，在危险因素方面存在重要的性别差异。我们的初步研究揭示了有自杀风险的成年ADHD患者与无自杀风险的患者之间的一些显着差异。然而,鉴于我们有限的样本量和局限性，我们希望我们的研究鼓励更大规模的研究进一步研究这种关系,以提高其普遍性.
