PDF(Pubmed)
Abstract：
Primary progressive apraxia of speech (PPAOS) is a neurodegenerative syndrome characterized by the progressive and initially isolated or predominant onset of difficulties in the planning/programming of movements necessary for speech production and can be accompanied by dysarthria. To date, no study has used an evidence-based treatment to address phonation control in patients with PPAOS. The aim of this study was to evaluate the feasibility and efficacy of LSVT LOUD® as a treatment for phonatory control in speakers with PPAOS. Three speakers with PPAOS received LSVT LOUD® therapy, and changes in phonatory control, voice quality and prosody were measured immediately, and one, four and eight weeks after the end of the treatment. Overall, the results suggest that the treatment is feasible and could improve voice quality, intensity, and control in some patients with PPAOS. The generalization of the results is also discussed.
摘要：
原发性进行性言语失用症（PPAOS）是一种神经退行性综合征，其特征是在言语产生所需的运动的计划/编程中出现进行性和最初孤立或主要的困难，并伴有构音障碍。迄今为止,没有研究使用循证治疗来解决PPAOS患者的发声控制问题.这项研究的目的是评估LSVTLOUD®作为PPAOS扬声器语音控制治疗的可行性和有效性。三名使用PPAOS的演讲者接受了LSVTLOUD®治疗，以及语音控制的变化，立即测量语音质量和韵律，还有一个,治疗结束后4周和8周。总的来说,结果表明，该治疗方法是可行的，可以改善嗓音质量，强度,和控制一些PPAOS患者。还讨论了结果的推广。
