关键词: Hypertrophic scar Inflammation Local flap Reticular dermis Z-plasty

Mesh : Humans Cicatrix, Hypertrophic / etiology therapy prevention & control Burns / complications therapy Skin Transplantation / methods Surgical Flaps Plastic Surgery Procedures / methods Risk Factors

来  源:   DOI:10.1016/j.cps.2024.02.001

Abstract:
Hypertrophic scars arise from burn injuries because of persistent inflammation in the reticular dermis. Several risk factors promote this chronic inflammation. One is tension on the burn wound/scar due to surrounding skin tightness and bodily movements. High estrogen levels and hypertension are also important systemic risk factors. Thus, to prevent burn wounds from developing into hypertrophic scars, it is important to focus on quickly resolving the reticular dermal inflammation. If conservative treatments are not effective and the hypertrophic scar transitions to scar contracture, surgical methods such as Z-plasty, full-thickness skin grafting, and local flaps are often used.
摘要:
由于网状真皮中持续的炎症,增生性疤痕是由烧伤引起的。几个危险因素促进这种慢性炎症。一种是由于周围的皮肤紧绷和身体运动引起的烧伤伤口/疤痕上的张力。高雌激素水平和高血压也是重要的全身性危险因素。因此,为了防止烧伤伤口发展成肥厚性疤痕,重要的是要专注于快速解决网状皮肤炎症。如果保守治疗无效,并且增生性瘢痕过渡到瘢痕挛缩,手术方法,如Z型成形术,全层植皮,和局部皮瓣经常使用。
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