嗅觉神经母细胞瘤模拟小细胞肺癌的分子异质性和谱系轨迹。
关键词: ASCL1 NEUROD1 POU2F3 RPM SCLC esthesioneuroblastoma neuroendocrine olfactory neuroblastoma plasticity tuft
Mesh : Animals Mice Small Cell Lung Carcinoma / genetics pathology metabolism Humans Esthesioneuroblastoma, Olfactory / genetics pathology Cell Lineage Lung Neoplasms / genetics pathology Basic Helix-Loop-Helix Transcription Factors / genetics metabolism Tumor Microenvironment Nose Neoplasms / genetics pathology Olfactory Mucosa / pathology metabolism Disease Models, Animal Tumor Suppressor Protein p53 / genetics metabolism
来 源:
DOI:10.1016/j.ccell.2024.05.003
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