Abstract：
Huntington\'s disease (HD) is a rare neurodegenerative disorder with a distinct phenotype, including involuntary movements, cognitive decline, and behavioral disturbances. Sleep disorder include insomnia, increased sleep onset latency, decrease in total sleep time with frequent nocturnal awakenings and excessive daytime sleepiness. Increased sleep motor activities and abnormal nocturnal agitation have been increasingly recognized as an important component affecting negatively the sleep quality. Here, we report a case of an intensification of diurnal choreic movement during the night, notably during REM-sleep in a patient with manifest HD. This case highlights the diversity of nocturnal sleep motor disorders encountered in HD.
摘要：
亨廷顿病（HD）是一种罕见的神经退行性疾病，具有独特的表型，包括非自愿运动，认知能力下降,和行为障碍。睡眠障碍包括失眠，睡眠发作潜伏期增加，总睡眠时间减少，夜间频繁觉醒和白天过度嗜睡。增加的睡眠运动活动和异常的夜间躁动越来越被认为是对睡眠质量产生负面影响的重要组成部分。这里,我们报告了一个夜间昼夜舞蹈运动加剧的案例，特别是在患有明显HD的患者的REM睡眠期间。此病例突出了HD中夜间睡眠运动障碍的多样性。
