Abstract：
UNASSIGNED: Recent studies have shown inconsistent results regarding the association between QRS characteristics and survival outcomes in patients with cardiac arrest and pulseless electrical activity (PEA) rhythms. This meta-analysis aimed to identify the usefulness of QRS width and frequency as prognostic tools for outcomes in patients with cardiac arrest and PEA rhythm.
UNASSIGNED: Extensive searches were conducted using Medline, Embase, and the Cochrane Library to find articles published from database inception to 4 June 2023. Studies that assessed the association between the QRS characteristics of cardiac arrest patients with PEA rhythm and survival outcomes were included. The Newcastle-Ottawa Scale was used to assess the methodological quality of the included studies.
UNASSIGNED: A total of 9727 patients from seven observational studies were included in this systematic review and meta-analysis. The wide QRS group (QRS ≥ 120 ms) was associated with significantly higher odds of mortality than the narrow QRS group (QRS < 120 ms) (odds ratio (OR) = 1.86, 95% confidence interval (CI) = 1.11-3.11, I2 = 58%). The pooled OR for mortality was significantly higher in patients with a QRS frequency of < 60/min than in those with a QRS frequency of ≥ 60/min (OR = 1.90, 95% CI = 1.19-3.02, I2 = 65%).
UNASSIGNED: Wide QRS width or low QRS frequency is associated with increased odds of mortality in patients with PEA cardiac arrest. These findings may be beneficial to guide the disposition of cardiac arrest patients with PEA during resuscitation.
UNASSIGNED: Extensive searches were conducted using Medline, Embase, and the Cochrane Library to find articles published from database inception to 4 June 2023. Studies that assessed the association between the QRS characteristics of cardiac arrest patients with PEA rhythm and survival outcomes were included. The Newcastle-Ottawa Scale was used to assess the methodological quality of the included studies.
UNASSIGNED: A total of 9727 patients from seven observational studies were included in this systematic review and meta-analysis. The wide QRS group (QRS ≥ 120 ms) was associated with significantly higher odds of mortality than the narrow QRS group (QRS < 120 ms) (odds ratio (OR) = 1.86, 95% confidence interval (CI) = 1.11-3.11, I2 = 58%). The pooled OR for mortality was significantly higher in patients with a QRS frequency of < 60/min than in those with a QRS frequency of ≥ 60/min (OR = 1.90, 95% CI = 1.19-3.02, I2 = 65%).
UNASSIGNED: Wide QRS width or low QRS frequency is associated with increased odds of mortality in patients with PEA cardiac arrest. These findings may be beneficial to guide the disposition of cardiac arrest patients with PEA during resuscitation.
摘要：
目的：最近的研究表明，关于心脏骤停和无脉性电活动（PEA）节律患者的QRS特征与生存结局之间的关系，结果不一致。这项荟萃分析旨在确定QRS宽度和频率作为心脏骤停和PEA节律患者预后工具的有用性。方法：使用Medline进行广泛的搜索，Embase,和Cochrane图书馆查找从数据库开始到2023年6月4日发表的文章。包括评估PEA心律心脏骤停患者QRS特征与生存结果之间相关性的研究。采用纽卡斯尔-渥太华量表评估纳入研究的方法学质量。结果：共纳入7项观察性研究的9,727例患者纳入本系统评价和荟萃分析。宽QRS组（QRS≥120ms）的死亡率明显高于窄QRS组（QRS<120ms）（比值比（OR）=1.86，95％置信区间（CI）=1.11-3.11，I2=58％）。QRS频率<60/min的患者的合并OR死亡率明显高于QRS频率≥60/min的患者（OR=1.90，95％CI=1.19-3.02，I2=65％）。结论：宽QRS宽度或低QRS频率与PEA心脏骤停患者死亡率增加相关。这些发现可能有助于指导PEA心脏骤停患者在复苏过程中的处置。
