PDF(Pubmed)
Abstract：
Musculoskeletal injuries such as equine osteoarthritis, osteoarticular defects, tendonitis/desmitis, and muscular disorders are prevalent among sport horses, with a fair prognosis for returning to exercise or previous performance levels. The field of equine medicine has witnessed rapid and fruitful development, resulting in a diverse range of therapeutic options for musculoskeletal problems. Staying abreast of these advancements can be challenging, prompting the need for a comprehensive review of commonly used and recent treatments. The aim is to compile current therapeutic options for managing these injuries, spanning from simple to complex physiotherapy techniques, conservative treatments including steroidal and non-steroidal anti-inflammatory drugs, hyaluronic acid, polysulfated glycosaminoglycans, pentosan polysulfate, and polyacrylamides, to promising regenerative therapies such as hemoderivatives and stem cell-based therapies. Each therapeutic modality is scrutinized for its benefits, limitations, and potential synergistic actions to facilitate their most effective application for the intended healing/regeneration of the injured tissue/organ and subsequent patient recovery. While stem cell-based therapies have emerged as particularly promising for equine musculoskeletal injuries, a multidisciplinary approach is underscored throughout the discussion, emphasizing the importance of considering various therapeutic modalities in tandem.
摘要：
肌肉骨骼损伤如马骨关节炎，骨关节缺损,肌腱炎/肌腱炎，肌肉疾病在运动马匹中普遍存在，对恢复锻炼或以前的表现水平有一个公平的预后。马医学领域发展迅速而卓有成效,导致肌肉骨骼问题的多种治疗选择。跟上这些进步可能是具有挑战性的，提示需要对常用和近期治疗方法进行全面审查。目的是编制当前治疗这些损伤的治疗方案，从简单到复杂的物理治疗技术，保守治疗包括类固醇和非甾体抗炎药，透明质酸，多硫酸化糖胺聚糖，戊聚糖多硫酸盐，和聚丙烯酰胺，有前途的再生疗法，如血液衍生物和基于干细胞的疗法。每种治疗方式都会被仔细审查其益处，局限性,和潜在的协同作用，以促进它们最有效地应用于受损组织/器官的预期愈合/再生和随后的患者恢复。虽然基于干细胞的疗法对于马的肌肉骨骼损伤特别有希望，在整个讨论中强调了多学科的方法，强调同时考虑各种治疗方式的重要性。
