PDF(Pubmed)
Abstract：
The Cannabis species is one of the potent ancient medicinal plants acclaimed for its medicinal properties and recreational purposes. The plant parts are used and exploited all over the world for several agricultural and industrial applications. For many years Cannabis spp. has proven to present a highly diverse metabolomic profile with a pool of bioactive metabolites used for numerous pharmacological purposes ranging from anti-inflammatory to antimicrobial. Cannabis sativa has since been an extensive subject of investigation, monopolizing the research. Hence, there are fewer studies with a comprehensive understanding of the composition of bioactive metabolites grown in different environmental conditions, especially C. indica and a few other Cannabis strains. These pharmacological properties are mostly attributed to a few phytocannabinoids and some phytochemicals such as terpenoids or essential oils which have been tested for antimicrobial properties. Many other discovered compounds are yet to be tested for antimicrobial properties. These phytochemicals have a series of useful properties including anti-insecticidal, anti-acaricidal, anti-nematicidal, anti-bacterial, anti-fungal, and anti-viral properties. Research studies have reported excellent antibacterial activity against Gram-positive and Gram-negative multidrug-resistant bacteria as well as methicillin-resistant Staphylococcus aureus (MRSA). Although there has been an extensive investigation on the antimicrobial properties of Cannabis, the antimicrobial properties of Cannabis on phytopathogens and aquatic animal pathogens, mostly those affecting fish, remain under-researched. Therefore, the current review intends to investigate the existing body of research on metabolomic profile and anti-microbial properties whilst trying to expand the scope of the properties of the Cannabis plant to benefit the health of other animal species and plant crops, particularly in agriculture.
摘要：
大麻物种是一种强大的古代药用植物，以其药用特性和娱乐目的而闻名。植物部件在世界各地用于多种农业和工业应用。多年来大麻属。已被证明具有用于从抗炎到抗微生物的许多药理学目的的生物活性代谢物池的高度多样化的代谢组学概况。此后，大麻一直是广泛的调查对象，垄断研究。因此，对在不同环境条件下生长的生物活性代谢物的组成有全面了解的研究较少，尤其是印度芽孢杆菌和其他一些大麻菌株。这些药理学性质主要归因于一些植物大麻素和一些植物化学物质,例如萜类或精油,其已经测试了抗微生物性质。许多其他发现的化合物尚未进行抗微生物性质的测试。这些植物化学物质具有一系列有用的特性，包括抗杀虫，抗杀螨剂,抗线虫,抗菌,抗真菌,和抗病毒特性。研究报告了对革兰氏阳性和革兰氏阴性多重耐药细菌以及耐甲氧西林金黄色葡萄球菌（MRSA）的优异抗菌活性。尽管对大麻的抗菌特性进行了广泛的研究，大麻对植物病原体和水生动物病原体的抗菌特性，主要是那些影响鱼类的，研究不足。因此,当前的审查旨在调查现有的代谢组学概况和抗微生物特性的研究机构，同时试图扩大大麻植物的特性范围，以有利于其他动物物种和植物作物的健康，尤其是在农业方面。
