PDF(Pubmed)
Abstract：
TAFRO syndrome (TS) is a recently recognized and heterogenous systemic disease characterized by a confluence of symptoms: thrombocytopenia (T), anasarca (A), fever (F), reticulin myelofibrosis (R), and organomegaly (O). First described in Japan in 2010, the pathogenesis remains unclear and includes various clinical conditions such as malignancies, rheumatologic disorders, infections, and \"Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal plasma cell disorder, and Skin changes\" (POEMS) syndrome. Due to its heterogeneous presentation and potential life-threatening delays in diagnosis, accurate diagnosis is crucial. According to the literature, no specific imaging modality has been recommended for the work-up of patients with suspected TS. Here, we report a case of TS and its management using 18F-FDG-PET/CT imaging as an attractive complementary diagnostic tool.
摘要：
TAFRO综合征（TS）是一种最近公认的异质性全身性疾病，其特征是症状汇合：血小板减少症（T），anasarca(A),发烧（F），网织蛋白骨髓纤维化（R），和器官肿大（O）。2010年在日本首次描述，发病机制尚不清楚，包括各种临床疾病，如恶性肿瘤，风湿病,感染,和“多发性神经病,器官肿大,内分泌疾病,单克隆浆细胞疾病，和皮肤变化（POEMS）综合征。由于其异质性表现和潜在的危及生命的诊断延迟，准确的诊断至关重要。根据文献,对于疑似TS的患者,没有推荐特定的影像学检查方法.这里,我们报告1例TS及其治疗,采用18F-FDG-PET/CT显像作为一种有吸引力的辅助诊断工具.
