Abstract:
Adenoid cystic/Basal-cell carcinoma (ACC/BCC) of the prostate is a rare histological type exhibiting various morphological characteristics and an optimal treatment has not yet been established. We report the case of a 63-year-old patient who complained of incomplete bladder emptying and recurrent urinary infection six months after transurethral resection of a high-grade urothelial bladder tumor. The clinical features, digital rectal examination, serum PSA levels, and multiparametric MRI did not refer to any suspicious prostatic lesions and cystoscopy revealed bladder neck hypertrophy, and yellowish zones in the prostatic urethra. Transurethral resection was performed due to these findings and histopathological analysis showed poorly differentiated ACC/BCC of the prostate. Even though there is no proven mutual correlation between ACC/BCC and urothelial bladder cancer, the appearance of obstructive urinary symptoms, bladder-neck hypertrophy, and macroscopic changes in prostatic urethra should be reconsidered for transurethral resection biopsy considering the possibility of ACC/BCC.
摘要:
前列腺的腺样囊性/基底细胞癌(ACC/BCC)是一种罕见的组织学类型,具有各种形态特征,尚未建立最佳治疗方法。我们报告了一名63岁的患者,该患者在经尿道切除高级别尿路上皮膀胱肿瘤后六个月抱怨膀胱排空不全和复发性尿路感染。临床特征,直肠指检,血清PSA水平,多参数MRI未提及任何可疑前列腺病变,膀胱镜检查显示膀胱颈肥大,和前列腺尿道中的淡黄色区域。由于这些发现,进行了经尿道切除术,组织病理学分析显示前列腺的ACC/BCC分化差。尽管ACC/BCC与膀胱尿路上皮癌之间没有被证实的相互关系,尿路阻塞症状的出现,膀胱颈肥大,考虑到ACC/BCC的可能性,经尿道电切活检应重新考虑前列腺尿道的宏观变化。