PDF(Pubmed)
Abstract：
Root-knot nematodes are polyphagous parasitic nematodes that cause severe losses in the agriculture worldwide. They enter the root in the elongation zone and subtly migrate to the root meristem where they reach the vascular cylinder and establish a feeding site called gall. Inside the galls they induce a group of transfer cells that serve to nurture them along their parasitic stage, the giant cells. Galls and giant cells develop through a process of post-embryogenic organogenesis that involves manipulating different genetic regulatory networks within the cells, some of them through hijacking some molecular transducers of established plant developmental processes, such as lateral root formation or root regeneration. Galls/giant cells formation involves different mechanisms orchestrated by the nematode´s effectors that generate diverse plant responses in different plant tissues, some of them include sophisticated mechanisms to overcome plant defenses. Yet, the plant-nematode interaction is normally accompanied to dramatic transcriptomic changes within the galls and giant cells. It is therefore expected a key regulatory role of plant-transcription factors, coordinating both, the new organogenesis process induced by the RKNs and the plant response against the nematode. Knowing the role of plant-transcription factors participating in this process becomes essential for a clear understanding of the plant-RKNs interaction and provides an opportunity for the future development and design of directed control strategies. In this review, we present the existing knowledge of the TFs with a functional role in the plant-RKN interaction through a comprehensive analysis of current scientific literature and available transcriptomic data.
摘要：
根结线虫是多食性寄生线虫，在全世界的农业中造成严重损失。它们进入伸长区的根，并巧妙地迁移到根分生组织，在那里它们到达血管圆柱体并建立一个称为胆汁的摄食部位。在虫卵内，它们诱导一组转移细胞，这些转移细胞在寄生阶段对它们进行培育，巨细胞.胆囊和巨细胞是通过胚胎发生后器官发生过程发展的，该过程涉及操纵细胞内不同的遗传调节网络，其中一些是通过劫持一些已建立的植物发育过程的分子传感器，如侧根形成或根再生。Galls/巨细胞的形成涉及由线虫效应子精心策划的不同机制，这些效应子在不同的植物组织中产生不同的植物反应。其中一些包括复杂的机制来克服植物防御。然而，植物与线虫的相互作用通常伴随着galls和巨细胞内的急剧转录组变化。因此，预计植物转录因子的关键调节作用，两者协调,RKN诱导的新器官发生过程和植物对线虫的反应。了解参与此过程的植物转录因子的作用对于清楚了解植物与RKNs的相互作用至关重要，并为将来开发和设计定向控制策略提供了机会。在这次审查中,通过对当前科学文献和可用转录组数据的综合分析，我们介绍了在植物-RKN相互作用中具有功能作用的TFs的现有知识。
