关键词: contact allergen contact dermatitis frontal fibrosing alopecia lichen planopilaris personal care products

来  源:   DOI:10.1097/JW9.0000000000000149   PDF(Pubmed)

Abstract:
UNASSIGNED: Frontal fibrosing alopecia (FFA) is a form of lichen planopilaris with an undetermined etiopathogenesis, predominantly affecting women. There is conflicting evidence as to whether contact allergens may play a role in the underlying etiology or progression of FFA.
UNASSIGNED: The aim of this study is to find the most common products that patients search for online, identify contact allergens present in these advertised over-the-counter hair products, and suggest their role in the development or exacerbation of FFA.
UNASSIGNED: We reviewed current research on this topic and then investigated common allergens found in over-the-counter hair products commonly used for hair regrowth.
UNASSIGNED: FFA\'s exact etiopathogenesis remains vastly unknown, however, current literature has reported an association between inflammatory skin conditions and FFA.
UNASSIGNED: The lack of published data on the function of contact allergens in FFA placed restrictions on our study.
UNASSIGNED: A survey-based analysis with a larger cohort is needed to further interpret the relationship between product use and FFA presentation based on contact allergens. More research on possible etiopathogenesis and the relationship between contact dermatitis and FFA may prevent further progression of a patient\'s disease, leading to an improvement in their quality of life.
摘要:
额叶纤维性脱发(FFA)是一种扁平苔藓,病因不明,主要影响女性。关于接触性过敏原是否可能在FFA的潜在病因或进展中起作用,存在矛盾的证据。
这项研究的目的是找到患者在网上搜索的最常见的产品,确定这些广告的非处方美发产品中存在的接触过敏原,并提出它们在FFA发展或恶化中的作用。
我们回顾了当前有关该主题的研究,然后调查了通常用于头发再生的非处方头发产品中发现的常见过敏原。
FFA的确切病因仍然未知,然而,目前的文献报道了炎性皮肤病与FFA之间的关联。
缺乏有关FFA中接触性过敏原功能的公开数据,这限制了我们的研究。
需要以更大的队列进行基于调查的分析,以进一步解释产品使用与基于接触性过敏原的FFA呈现之间的关系。更多关于可能的病因和接触性皮炎与FFA之间关系的研究可能会阻止患者疾病的进一步进展,改善他们的生活质量。
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