Abstract:
Autoimmune polyendocrine syndromes (APS) encompass m ultiple e ndocrin e gland ins ufficiencies asso ci ated wit h auto immune disease. This c as e report underscores the importance of recognising the association between latent auto immune di a betes of ad ults (LADA) and type 3 polyglandular syndrome. A 42-year-old man belonging to R awalpi ndi, Pakistan, p resented to th e out patient department (OPD) of Ali Medi cal Centre, Islamab ad, i n Januar y 2023 with the complaints o f e xtreme thirs t and frequent urination. The patient reported consistently raised app etite an d eating four to five meals a day along with abrupt weight loss, dry mouth, fatigue occasional dizziness, an d dyspnoea. He was diagno s ed with type 3 polygla ndular syndrome w ith associat io n of LADA. Daily administration of 10 units of glargine insulin, along with six units of rapid-acting insulin, was prescribed. The patient\'s H bA1c level reduce d in a few months afte r succe ssive follow-up. Patients who exhi bit uncontrol led diabe tes despite dietar y and oral hypoglycaemic management should be further investigated for multiple au toimmune endocrine disorders.
摘要:
自身免疫性多内分泌综合征(APS)包括与自身免疫性疾病相关的多重腺体。这份报告强调了认识到潜在的成人自身免疫性疾病(LADA)与3型多腺综合征之间联系的重要性。一名42岁的男子属于Rawalpindi,巴基斯坦,p对阿里医疗中心的病人部门(OPD)表示不满,伊斯兰广告,于2023年1月1日,有关于xtremethirs和尿频的抱怨。患者报告说,每天持续增加应用程序,每天吃四到五餐,同时体重突然下降,口干,疲劳偶尔头晕,呼吸困难.他被诊断为与LADA相关的3型多glandular综合征。每日服用10单位甘精胰岛素,以及六个单位的速效胰岛素,是开的。成功随访后几个月,患者的HbA1c水平降低。尽管有饮食和口服低血糖管理,但仍未控制糖尿病的患者应进一步调查多种免疫内分泌紊乱。