关键词: IVIG Stevens-Johnson syndrome autoimmune diseases bullous dermatoses dermatomyositis immunomodulation intravenous immunoglobulin

Mesh : Humans Immunoglobulins, Intravenous / therapeutic use administration & dosage Skin Diseases / drug therapy Immunologic Factors / therapeutic use administration & dosage

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Abstract:
Intravenous immune globulin (IVIG) is a manufactured blood product commonly used to treat immunodeficiency syndromes, inflammatory disorders, and autoimmune diseases of the skin. The use of IVIG in dermatology has evolved and expanded over time, serving as a useful therapeutic intervention for several inflammatory skin disorders. In addition to demonstrating efficacy in treating several cutaneous pathologies, IVIG also mitigates the need for steroids or other immunosuppressant medications in many dermatologic diseases. This review highlights the evidence for IVIG use across several dermatologic conditions, emphasizing the dosing regimens and safety considerations.
摘要:
静脉免疫球蛋白(IVIG)是一种常用于治疗免疫缺陷综合征的人造血液制品,炎症性疾病,和皮肤自身免疫性疾病。IVIG在皮肤病学中的使用随着时间的推移而发展和扩大,作为几种炎症性皮肤病的有用治疗干预措施。除了证明治疗几种皮肤病变的功效外,IVIG还减轻了许多皮肤病中对类固醇或其他免疫抑制剂药物的需要。这篇评论强调了IVIG在几种皮肤病中使用的证据,强调给药方案和安全性考虑。
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