Abstract：
Nine compounds were isolated and identified from ethanolic extracts of Saposhnikovia divaricata, including one new alkaloid (1), one new pentacyclic triterpenoid (9), and seven known alkaloids (2-8). Structural elucidation of compounds 1 and 9 was established by 1D and 2D NMR spectra referring to the literature, together with high-resolution mass spectrometric analysis. All compounds were evaluated for antiproliferative activity against two cancer cell lines (LN229, A549) in vitro. Compounds (1-9) showed no significant antiproliferative activity.
摘要：
从防风的乙醇提取物中分离并鉴定了9种化合物，包括一种新的生物碱（1），一种新的五环三萜（9），和七种已知的生物碱（2-8）。化合物1和9的结构阐明通过参考文献的1D和2DNMR光谱建立，与高分辨率质谱分析。在体外评价所有化合物对两种癌细胞系(LN229,A549)的抗增殖活性。化合物(1-9)不显示显著的抗增殖活性。
