PDF(Pubmed)
Abstract：
UNASSIGNED: Diabetes in the 21st century presents one of the greatest burdens of disease on the global population. Digitally mediated interventions have become imperative in alleviating this disease epidemic. We aimed to systematically review randomized controlled trials (RCTs) on different health technologies for preventing Type 2 diabetes mellitus, and their efficacy in decreasing diabetes risk-related outcomes in at-risk patients in comparison to standard care.
UNASSIGNED: Five electronic databases were searched between October 2021 and December 2022. Studies including digital health technology interventions used for preventing diabetes development by reducing diabetes risk-related outcomes in at-risk adults (⩾18 years) were identified. Data on glycemic levels, incidence of T2DM, weight, and intervention descriptions were extracted, and the risk of bias (ROB) was assessed.
UNASSIGNED: Nine studies met the inclusion criteria and 5 studies (56%) achieved clinically significant outcomes in at least one of the following: decreased weight (22%), glycemic levels (22%), or incidence of T2DM (11%). Two of the 3 (67%) computer-based interventions effectively reduced the HbA1c levels and mean weight of their study population, and 3 of 6 (50%) mobile based interventions (text messages, mobile app, and telehealth) decreased the incidence of T2DM and HbA1c levels. Four studies each had an overall low ROB and one had a high ROB due to attrition.
UNASSIGNED: Preliminary evidence identified in our review demonstrated that health technologies for diabetes prevention are effective for improving diabetes risk-related outcomes. Future research into digital technology protocol and studies of longer duration and more diverse populations are needed for clinical feasibility.
Role of Digital technology in Diabetes prevention In the 21st century, diabetes has become a major health challenge globally. To address this, we conducted a systematic review, looking at studies that used digital interventions to prevent Type 2 diabetes mellitus (T2DM) and how effective they are compared to standard care. In this study, we searched electronic databases from October 2021 to December 2022 and identified 9 studies that met our criteria. These studies focused on adults aged 18 and above who were at risk of developing diabetes. We looked at outcomes like glucose concentrations, T2DM incidence, and weight, and assessed the risk of bias in each study. The results showed that more than half of the studies showed significant outcomes. For instance, some interventions led to decreased weight, lower glucose concentrations, or reduced incidence of T2DM. Computer-based interventions and mobile-based interventions (including text messages, mobile apps, and telehealth) were particularly effective in improving these outcomes. In conclusion, our review suggests that digital health technologies can be effective in preventing diabetes and improving related outcomes. However, we note that more research is needed, especially looking at diverse populations and longer study durations, to confirm the clinical feasibility of these digital interventions for diabetes prevention. This is a promising step forward in using technology to tackle the growing diabetes epidemic, offering new ways to support individuals at risk and improve their health outcomes.
UNASSIGNED: Five electronic databases were searched between October 2021 and December 2022. Studies including digital health technology interventions used for preventing diabetes development by reducing diabetes risk-related outcomes in at-risk adults (⩾18 years) were identified. Data on glycemic levels, incidence of T2DM, weight, and intervention descriptions were extracted, and the risk of bias (ROB) was assessed.
UNASSIGNED: Nine studies met the inclusion criteria and 5 studies (56%) achieved clinically significant outcomes in at least one of the following: decreased weight (22%), glycemic levels (22%), or incidence of T2DM (11%). Two of the 3 (67%) computer-based interventions effectively reduced the HbA1c levels and mean weight of their study population, and 3 of 6 (50%) mobile based interventions (text messages, mobile app, and telehealth) decreased the incidence of T2DM and HbA1c levels. Four studies each had an overall low ROB and one had a high ROB due to attrition.
UNASSIGNED: Preliminary evidence identified in our review demonstrated that health technologies for diabetes prevention are effective for improving diabetes risk-related outcomes. Future research into digital technology protocol and studies of longer duration and more diverse populations are needed for clinical feasibility.
Role of Digital technology in Diabetes prevention In the 21st century, diabetes has become a major health challenge globally. To address this, we conducted a systematic review, looking at studies that used digital interventions to prevent Type 2 diabetes mellitus (T2DM) and how effective they are compared to standard care. In this study, we searched electronic databases from October 2021 to December 2022 and identified 9 studies that met our criteria. These studies focused on adults aged 18 and above who were at risk of developing diabetes. We looked at outcomes like glucose concentrations, T2DM incidence, and weight, and assessed the risk of bias in each study. The results showed that more than half of the studies showed significant outcomes. For instance, some interventions led to decreased weight, lower glucose concentrations, or reduced incidence of T2DM. Computer-based interventions and mobile-based interventions (including text messages, mobile apps, and telehealth) were particularly effective in improving these outcomes. In conclusion, our review suggests that digital health technologies can be effective in preventing diabetes and improving related outcomes. However, we note that more research is needed, especially looking at diverse populations and longer study durations, to confirm the clinical feasibility of these digital interventions for diabetes prevention. This is a promising step forward in using technology to tackle the growing diabetes epidemic, offering new ways to support individuals at risk and improve their health outcomes.
摘要：
21世纪的糖尿病是全球人口最大的疾病负担之一。数字介导的干预措施已成为缓解这种疾病流行的当务之急。我们旨在系统回顾关于预防2型糖尿病的不同健康技术的随机对照试验(RCTs)。与标准治疗相比，它们在降低高危患者糖尿病风险相关结局方面的疗效。
■在2021年10月至2022年12月之间搜索了五个电子数据库。确定了包括数字健康技术干预措施在内的研究，这些干预措施用于通过降低高危成年人（18岁）的糖尿病风险相关结果来预防糖尿病的发展。关于血糖水平的数据，2型糖尿病的发病率,体重,并提取干预描述，并评估偏倚风险(ROB)。
■9项研究符合纳入标准，5项研究（56%）在以下至少一项方面取得了临床显著结果：体重减轻（22%），血糖水平（22%），或T2DM发病率（11%）。3个（67％）基于计算机的干预措施中的两个有效地降低了研究人群的HbA1c水平和平均体重，6个中的3个(50%)基于移动的干预(短信，移动应用程序，和远程健康）降低了T2DM和HbA1c水平的发病率。四项研究均具有总体较低的ROB，一项由于损耗而具有较高的ROB。
■在我们的综述中确定的初步证据表明，预防糖尿病的健康技术对于改善与糖尿病风险相关的结果是有效的。临床可行性需要对数字技术协议进行未来研究以及对更长时间和更多样化人群的研究。
21世纪数字技术在糖尿病预防中的作用，糖尿病已成为全球面临的重大健康挑战。为了解决这个问题，我们进行了系统的审查，查看使用数字干预措施预防2型糖尿病（T2DM）的研究，以及它们与标准护理相比的有效性。在这项研究中,我们检索了2021年10月至2022年12月的电子数据库,确定了9项符合我们标准的研究.这些研究集中于有患糖尿病风险的18岁及以上的成年人。我们研究了葡萄糖浓度等结果，T2DM发病率,和体重,并评估了每项研究的偏倚风险。结果显示，超过一半的研究显示出显著的结果。例如,一些干预措施导致体重下降，降低葡萄糖浓度，或降低T2DM的发病率。基于计算机的干预和基于移动的干预(包括短信，移动应用程序，和远程医疗)在改善这些结果方面特别有效。总之,我们的综述表明,数字健康技术可有效预防糖尿病并改善相关结局.然而,我们注意到需要更多的研究，尤其是观察不同的人群和更长的研究时间，证实这些数字干预措施用于糖尿病预防的临床可行性。这是利用技术来应对日益增长的糖尿病流行的一个有希望的步骤，提供新的方法来支持处于危险中的个人并改善他们的健康结果。
■在2021年10月至2022年12月之间搜索了五个电子数据库。确定了包括数字健康技术干预措施在内的研究，这些干预措施用于通过降低高危成年人（18岁）的糖尿病风险相关结果来预防糖尿病的发展。关于血糖水平的数据，2型糖尿病的发病率,体重,并提取干预描述，并评估偏倚风险(ROB)。
■9项研究符合纳入标准，5项研究（56%）在以下至少一项方面取得了临床显著结果：体重减轻（22%），血糖水平（22%），或T2DM发病率（11%）。3个（67％）基于计算机的干预措施中的两个有效地降低了研究人群的HbA1c水平和平均体重，6个中的3个(50%)基于移动的干预(短信，移动应用程序，和远程健康）降低了T2DM和HbA1c水平的发病率。四项研究均具有总体较低的ROB，一项由于损耗而具有较高的ROB。
■在我们的综述中确定的初步证据表明，预防糖尿病的健康技术对于改善与糖尿病风险相关的结果是有效的。临床可行性需要对数字技术协议进行未来研究以及对更长时间和更多样化人群的研究。
21世纪数字技术在糖尿病预防中的作用，糖尿病已成为全球面临的重大健康挑战。为了解决这个问题，我们进行了系统的审查，查看使用数字干预措施预防2型糖尿病（T2DM）的研究，以及它们与标准护理相比的有效性。在这项研究中,我们检索了2021年10月至2022年12月的电子数据库,确定了9项符合我们标准的研究.这些研究集中于有患糖尿病风险的18岁及以上的成年人。我们研究了葡萄糖浓度等结果，T2DM发病率,和体重,并评估了每项研究的偏倚风险。结果显示，超过一半的研究显示出显著的结果。例如,一些干预措施导致体重下降，降低葡萄糖浓度，或降低T2DM的发病率。基于计算机的干预和基于移动的干预(包括短信，移动应用程序，和远程医疗)在改善这些结果方面特别有效。总之,我们的综述表明,数字健康技术可有效预防糖尿病并改善相关结局.然而,我们注意到需要更多的研究，尤其是观察不同的人群和更长的研究时间，证实这些数字干预措施用于糖尿病预防的临床可行性。这是利用技术来应对日益增长的糖尿病流行的一个有希望的步骤，提供新的方法来支持处于危险中的个人并改善他们的健康结果。
