PDF(Pubmed)
Abstract：
A primary benign hepatic schwannoma is an extremely rare disease with a good prognosis. A 55-year-old man with chronic hepatitis B was referred to our hospital because of jaundice, weight loss, and a hepatic lesion found during an ultrasound examination. Magnetic resonance image revealed a 55 × 120 mm solid mass lesion in the segment V and VIII of the liver. The mass extended directly to the segmental biliary ducts and common hepatic duct, causing obstruction of the biliary duct and upstream dilatation, particularly in the left liver lobe. Following the insertion of a percutaneous transhepatic biliary drainage, a biopsy was performed under ultrasound guidance. Histological examination confirmed a benign schwannoma, identified by characteristic pathological findings and positive immunoreactions with S-100 protein, but negative for c-kit, CD117, or CD34. The patient\'s tumor was removed and upon examination, it was discovered to be a mass filled with pinkish-yellow fluid, measuring 12 × 5 × 5 cm. This is the first known case of a benign schwannoma in the liver parenchyma of a patient with chronic hepatitis B. Furthermore, most previous cases of benign liver schwannomas have reported a smaller size than this case, which is slightly larger.
摘要：
原发性良性肝神经鞘瘤是一种极其罕见的疾病，预后良好。一名55岁的慢性乙型肝炎男子因黄疸被转诊到我们医院，减肥,和超声检查时发现的肝脏病变。磁共振图像显示肝脏V和VIII段有55×120mm的实体肿块病变。肿块直接延伸至节段胆管和总肝管，导致胆管阻塞和上游扩张，特别是在左肝叶。在插入经皮肝穿刺胆道引流术后，在超声引导下进行活检.组织学检查证实为良性神经鞘瘤,通过特征性病理发现和S-100蛋白阳性免疫反应鉴定，但对c-kit不利,CD117或CD34。患者的肿瘤被切除，经检查，它被发现是一个充满粉红色黄色液体的肿块，测量12×5×5厘米。这是第一个已知的病例的良性神经鞘瘤在肝实质的慢性乙型肝炎患者。大多数以前的良性肝神经鞘瘤病例都报告了比这个病例更小的大小，稍微大一点。
