Abstract：
BACKGROUND: The use of prostheses in the oral cavity creates favorable conditions for Candida colonization, which may subsequently lead to Candida-associated denture stomatitis (CADS). Due to its many contributing factors and frequent relapses, CADS is difficult to manage. Given the rise in drug resistance among fungal species, it is critical to develop new therapeutic approaches, reduce the required dosage of medications, and minimize the toxicity and side effects of therapy.
CONCLUSIONS: Salivary lactoferrin, a multifunctional glycoprotein, is thought to be the first line of defense against microbial invasion of mucosal surfaces.
CONCLUSIONS: Current research emphasizes the capability of lactoferrin and its derivatives to eliminate a broad spectrum of Candida species. It may be an appealing option for use in monotherapy or in combination with common medications for oral stomatitis treatment. This review provides an overview of the current understanding of lactoferrin\'s anti-fungal effects in oral candidiasis.
CONCLUSIONS: Salivary lactoferrin, a multifunctional glycoprotein, is thought to be the first line of defense against microbial invasion of mucosal surfaces.
CONCLUSIONS: Current research emphasizes the capability of lactoferrin and its derivatives to eliminate a broad spectrum of Candida species. It may be an appealing option for use in monotherapy or in combination with common medications for oral stomatitis treatment. This review provides an overview of the current understanding of lactoferrin\'s anti-fungal effects in oral candidiasis.
摘要：
背景：在口腔中使用假体为念珠菌定植创造了有利条件，随后可能导致念珠菌相关义齿口炎（CADS）。由于其许多促成因素和频繁复发，CADS很难管理。鉴于真菌物种之间耐药性的上升，开发新的治疗方法至关重要，减少所需的药物剂量，并尽量减少治疗的毒性和副作用。
结论：唾液乳铁蛋白，多功能糖蛋白,被认为是抵抗粘膜表面微生物入侵的第一道防线。
结论：目前的研究强调乳铁蛋白及其衍生物消除广谱念珠菌的能力。它可能是用于单一疗法或与用于口腔口腔炎治疗的常见药物组合的有吸引力的选择。本文综述了目前对乳铁蛋白在口腔念珠菌病中的抗真菌作用的认识。
结论：唾液乳铁蛋白，多功能糖蛋白,被认为是抵抗粘膜表面微生物入侵的第一道防线。
结论：目前的研究强调乳铁蛋白及其衍生物消除广谱念珠菌的能力。它可能是用于单一疗法或与用于口腔口腔炎治疗的常见药物组合的有吸引力的选择。本文综述了目前对乳铁蛋白在口腔念珠菌病中的抗真菌作用的认识。
