Abstract：
Objective: This study aimed to investigate the effectiveness of prophylactic photobiomodulation (PBM) in reducing postinflammatory hyperpigmentation (PIH) induced by carbon dioxide (CO2) laser resurfacing in a patient with periorbital syringomas. Background: PIH is a common condition characterized by abnormal skin pigmentation after an inflammatory process occurring in up to 20-30% of patients undergoing CO2 laser resurfacing. Methods: The patient was treated with PBM using a pulsed home-use device at 630 nm before and after CO2 laser treatment. The patient was asked to treat the right periorbital area before and after the CO2 laser treatment, which was continued once a day for 2 consecutive weeks. Results: At 12 weeks, PIH was significantly reduced on the treated side compared with the contralateral untreated side (leading to persistent erythema at 6 months). Conclusions: This is the first report of prophylactic treatment of CO2 laser-induced dyschromia using PBM.
摘要：
目的：本研究旨在探讨预防性光生物调节（PBM）在减少眼眶周围汗管瘤患者二氧化碳（CO2）激光表面置换引起的炎症后色素沉着（PIH）中的作用。背景：PIH是一种常见病，其特征是在多达20-30％的接受CO2激光表面修复的患者中发生炎症过程后皮肤色素沉着异常。方法：在CO2激光治疗前后，使用630nm的脉冲家用设备对患者进行PBM治疗。患者被要求在CO2激光治疗前后治疗右眶周区域，连续2周，每天一次。结果：12周时，与对侧未治疗侧相比，治疗侧的PIH显着降低（导致6个月时持续出现红斑）。结论：这是使用PBM预防性治疗CO2激光诱发的色素异常的首次报道。
