Abstract：
BACKGROUND: Racial inequities in HIV in the United States (US) are pervasive. Pre-exposure prophylaxis (PrEP) is one of the most effective yet underutilized HIV prevention strategies, and stark inequities in PrEP uptake exist. Lack of access to PrEP clinics is a major barrier to access that could be overcome by integrating pharmacists into the provision of PrEP services including prescribing and dispensing.
METHODS: A number of reviews have shown promise in folding pharmacies into the expansion of PrEP services, but this review extends those by examining the implementation science evidence of pharmacist-led PrEP services in the US. We reviewed literature over the past five years of the implementation science of pharmacist PrEP services (2018-2023) and present seminal findings in this area.
RESULTS: Only two studies are anchored within an implementation science framework despite all studies assessing common implementation science constructs. Overwhelming evidence supports feasibility and adoption of PrEP services in pharmacies yet gaps in workflow integration, scalability and sustainability exist.
CONCLUSIONS: Continuing to build the implementation science evidence of pharmacy-based PrEP services is critical to standardize our measures across varying contexts and inform policy efforts that support pharmacy-based PrEP services.
METHODS: A number of reviews have shown promise in folding pharmacies into the expansion of PrEP services, but this review extends those by examining the implementation science evidence of pharmacist-led PrEP services in the US. We reviewed literature over the past five years of the implementation science of pharmacist PrEP services (2018-2023) and present seminal findings in this area.
RESULTS: Only two studies are anchored within an implementation science framework despite all studies assessing common implementation science constructs. Overwhelming evidence supports feasibility and adoption of PrEP services in pharmacies yet gaps in workflow integration, scalability and sustainability exist.
CONCLUSIONS: Continuing to build the implementation science evidence of pharmacy-based PrEP services is critical to standardize our measures across varying contexts and inform policy efforts that support pharmacy-based PrEP services.
摘要：
背景：在美国，艾滋病毒的种族不平等现象普遍存在。暴露前预防（PrEP）是最有效但未得到充分利用的艾滋病毒预防策略之一。PrEP吸收存在明显的不平等现象。缺乏进入PrEP诊所的机会是进入的主要障碍，可以通过将药剂师纳入包括处方和配药在内的PrEP服务来克服。
方法：许多评论已显示出在折叠药房扩展PrEP服务方面的希望，但是本综述通过研究美国药剂师主导的PrEP服务的实施科学证据来扩展这些研究.我们回顾了过去五年来药剂师PrEP服务实施科学（2018-2023）的文献，并介绍了该领域的开创性发现。
结果：尽管所有研究都评估了共同的实施科学结构，但只有两项研究是在实施科学框架内进行的。压倒性的证据支持药房中PrEP服务的可行性和采用，但在工作流集成方面存在差距，存在可扩展性和可持续性。
结论：继续建立基于药学的PrEP服务的实施科学证据对于在不同情况下标准化我们的措施并为支持基于药学的PrEP服务的政策努力提供信息至关重要。
方法：许多评论已显示出在折叠药房扩展PrEP服务方面的希望，但是本综述通过研究美国药剂师主导的PrEP服务的实施科学证据来扩展这些研究.我们回顾了过去五年来药剂师PrEP服务实施科学（2018-2023）的文献，并介绍了该领域的开创性发现。
结果：尽管所有研究都评估了共同的实施科学结构，但只有两项研究是在实施科学框架内进行的。压倒性的证据支持药房中PrEP服务的可行性和采用，但在工作流集成方面存在差距，存在可扩展性和可持续性。
结论：继续建立基于药学的PrEP服务的实施科学证据对于在不同情况下标准化我们的措施并为支持基于药学的PrEP服务的政策努力提供信息至关重要。
