PDF(Pubmed)
Abstract：
UNASSIGNED: Oral immunotherapy (OIT) is a promising allergen-specific approach in the management of food allergy; however, studies on OIT for allergic rhinitis (AR) have rarely been reported. The purpose of this study is to evaluate the efficacy and safety of OIT using enteric-coated capsules for AR induced by house dust mites.
UNASSIGNED: A total of 49 patients with AR were enrolled, including 25 who received subcutaneous immunotherapy (SCIT) and 24 who received OIT. The clinical efficacy and safety in both groups were evaluated.
UNASSIGNED: After 1 year of treatment, both SCIT and OIT demonstrated significant therapeutic effects. OIT was found to be more effective than SCIT in reducing the total AR symptom score and improving the results of nasal provocation tests. Local and systemic adverse reactions were observed in the SCIT group, while none were reported in the OIT group.
UNASSIGNED: OIT is an effective and safe treatment for mite-induced AR.
UNASSIGNED: A total of 49 patients with AR were enrolled, including 25 who received subcutaneous immunotherapy (SCIT) and 24 who received OIT. The clinical efficacy and safety in both groups were evaluated.
UNASSIGNED: After 1 year of treatment, both SCIT and OIT demonstrated significant therapeutic effects. OIT was found to be more effective than SCIT in reducing the total AR symptom score and improving the results of nasal provocation tests. Local and systemic adverse reactions were observed in the SCIT group, while none were reported in the OIT group.
UNASSIGNED: OIT is an effective and safe treatment for mite-induced AR.
摘要：
■口服免疫疗法（OIT）是治疗食物过敏的一种有前途的过敏原特异性方法；然而，关于OIT治疗过敏性鼻炎（AR）的研究很少报道。这项研究的目的是评估使用肠溶衣胶囊治疗屋尘螨引起的AR的OIT的有效性和安全性。
■共纳入49例AR患者，其中25人接受皮下免疫治疗（SCIT），24人接受OIT。评价两组的临床疗效和安全性。
■治疗1年后，SCIT和OIT均表现出显著的治疗效果.发现OIT在降低总AR症状评分和改善鼻激发试验结果方面比SCIT更有效。观察SCIT组的局部和全身不良反应,而OIT组没有报告。
■OIT是治疗螨引起的AR的有效且安全的治疗方法。
■共纳入49例AR患者，其中25人接受皮下免疫治疗（SCIT），24人接受OIT。评价两组的临床疗效和安全性。
■治疗1年后，SCIT和OIT均表现出显著的治疗效果.发现OIT在降低总AR症状评分和改善鼻激发试验结果方面比SCIT更有效。观察SCIT组的局部和全身不良反应,而OIT组没有报告。
■OIT是治疗螨引起的AR的有效且安全的治疗方法。
