关键词: National Cancer Database epidemiology lymph node medical dermatology oncology sebaceous carcinoma surgery treatment

来  源:   DOI:10.1016/j.jdin.2024.03.012   PDF(Pubmed)

Abstract:
UNASSIGNED: Sebaceous carcinoma is a rare cancer, and little is known about its current epidemiology and treatment. This is particularly true for sebaceous carcinomas of the trunk and extremities.
UNASSIGNED: We present a database analysis of sebaceous carcinoma cases to further delineate demographics, location, tumor characteristics, and treatment modalities among patients diagnosed with these tumors.
UNASSIGNED: The National Cancer Database was queried for cases of sebaceous carcinoma between 2004 and 2016. 3211 cases were analyzed for descriptive and comparative statistics.
UNASSIGNED: Twenty-six percent of sebaceous carcinomas were found on the trunk and extremities. Tumors on the trunk and extremities were more likely to be larger than tumors on the head and neck, with 8% being greater than 50 mm (P < .001). Tumors on the trunk and extremities were more likely to be well differentiated (P < .001) and have fewer lymph node metastases (P < .001). Surgery was the primary treatment modality for tumors, followed by radiotherapy and rarely chemotherapy.
UNASSIGNED: Sebaceous cancer is a poorly understood entity. We demonstrated that trunk and extremity tumors tend to be larger and more differentiated than those of the head and neck. Treatment practices are varied at this time, but surgery is the primary modality.
摘要:
皮脂腺癌是一种罕见的癌症,对其目前的流行病学和治疗知之甚少。对于躯干和四肢的皮脂腺癌尤其如此。
我们提供了皮脂腺癌病例的数据库分析,以进一步描绘人口统计学,location,肿瘤特征,以及诊断为这些肿瘤的患者的治疗方式。
国家癌症数据库查询了2004年至2016年之间的皮脂腺癌病例。对3211例病例进行描述性和比较统计学分析。
在躯干和四肢发现了26%的皮脂腺癌。躯干和四肢的肿瘤比头颈部的肿瘤更大,8%大于50mm(P<.001)。躯干和四肢的肿瘤更可能分化良好(P<.001),淋巴结转移较少(P<.001)。手术是肿瘤的主要治疗方式,其次是放疗和很少化疗。
皮脂腺癌是一种鲜为人知的实体。我们证明,躯干和四肢肿瘤往往比头颈部肿瘤更大,更分化。此时的治疗方法多种多样,但手术是最主要的方式.
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