关键词: orthopedic pleomorphic radiotherapy sarcoma thigh

来  源:   DOI:10.7759/cureus.58685   PDF(Pubmed)

Abstract:
The undifferentiated pleomorphic sarcoma (UPS) is a rare malignant tumor of mesenchymal origin. Poorly differentiated tumor cells, which might take the form of giant cells, histiocytes, or spindle-shaped cells, make up the UPS variant of sarcomas. If soft tissue tumors enlarge and turn malignant, they may become an issue. Sarcoma is diagnosed by several tests, such as a physical examination, MRI, CT scan, or ultrasound. A biopsy yields information regarding the grade and subtype of the sarcoma and is required for a clear diagnosis. Chemotherapy, radiation therapy, and broad-margin excision are the standard treatments for cancers of the bone. UPS often appears in people between 50 and 70 years old. Yet, here we report a 40-year-old male diagnosed with UPS. Our goal is to discuss how unique our case is in comparison to others, as well as the available diagnostic and therapeutic alternatives in such cases.
摘要:
未分化多形性肉瘤(UPS)是一种罕见的间充质起源的恶性肿瘤。分化差的肿瘤细胞,可能采取巨细胞的形式,组织细胞,或者纺锤形细胞,构成肉瘤的UPS变体。如果软组织肿瘤增大并变成恶性,他们可能会成为一个问题。通过几次检查可以诊断出肉瘤,比如体检,MRI,CT扫描,或超声波。活检可产生有关肉瘤等级和亚型的信息,并且是明确诊断所必需的。化疗,放射治疗,广泛切缘切除是骨癌的标准治疗方法。UPS经常出现在50至70岁的人群中。然而,在这里,我们报告一名40岁的男性被诊断为UPS。我们的目标是讨论我们的案例与其他案例相比有多独特,以及在这种情况下可用的诊断和治疗替代方案。
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