PDF(Pubmed)
Abstract：
Persistent fetal vasculature (PFV) is a rare ocular developmental disorder resulting from incomplete apoptosis of the embryonic hyaloid vasculature during the in-utero period. Variability in the development and regression of hyaloid vasculature is responsible for the wide range of clinical presentation of the disorder. PFV may manifest as anterior segment abnormalities (cataract, glaucoma, microphthalmia, elongated ciliary process with central traction, retrolental membrane, and shallow anterior chamber), posterior segment abnormalities (vitreous stalk, preretinal membranes, optic hypoplasia, and retinal folds), or with a combined anteroposterior disease. The most common associated clinical feature is leukocoria with microphthalmia and usually unilateral presentation. Most of the cases have poor visual prognosis and present early in childhood. Association with myopia is a very rare and atypical presentation, especially unilateral cases which may present later in life and have a good visual prognosis. Hereby, we present a case of a 27-year-old young adult male with unilateral atypical myopic posterior PFV with anisometropic amblyopia and good functional vision in the right eye.
摘要：
持续性胎儿脉管系统（PFV）是一种罕见的眼部发育障碍，是由于子宫内胚胎类脉管系统的不完全凋亡而引起的。玻璃样脉管系统的发育和消退的变异性是该疾病的广泛临床表现的原因。PFV可能表现为眼前节异常（白内障，青光眼,小眼症,中央牵引延长睫状突，后膜，和浅前房)，后段异常(玻璃体柄，视网膜前膜,视神经发育不全,和视网膜褶皱)，或伴有前后疾病。最常见的相关临床特征是伴有小眼症的白斑，通常是单侧表现。大多数病例的视力预后较差，并在儿童早期出现。与近视的关联是一种非常罕见和不典型的表现，尤其是单侧病例，可能出现在以后的生活和有良好的视觉预后。特此,我们介绍了一例27岁的年轻成年男性,患有单侧非典型近视后PFV伴屈光参差性弱视,右眼功能视力良好.
