PDF(Pubmed)
Abstract：
Purpose: To describe the clinical course of 3 patients with Stickler syndrome found on fluorescein angiography (FA) to have nonperfusion of the peripheral retina. Methods: Three patients with confirmed Stickler syndrome were examined under anesthesia. Genetic testing and FA were performed. Results: Each patient had characteristic ocular findings of Stickler syndrome, including high myopia with vitreoretinal degeneration. FA was performed on each patient and showed 360 degrees of nonperfusion of the retinal periphery in all eyes, with mild leakage in Case 3. Conclusions: The current series presents evidence of peripheral retinal nonperfusion in 3 consecutive patients with Stickler syndrome. Based on these findings, the authors recommend adopting FA as a standard imaging modality and using laser photocoagulation to treat the areas of retinal nonperfusion for all patients with Stickler syndrome.
摘要：
目的：描述3例荧光素血管造影（FA）发现周围视网膜无灌注的Stickler综合征患者的临床过程。方法:对3例确诊的Stickler综合征患者进行麻醉检查。进行基因检测和FA。结果：每位患者都有Stickler综合征的特征性眼部表现，包括高度近视伴玻璃体视网膜变性。对每位患者进行了FA检查，显示所有眼睛的视网膜周边无灌注360度，在情况3中轻度泄漏。结论：本系列提供了3例连续Stickler综合征患者的周边视网膜无灌注的证据。基于这些发现,作者建议对所有Stickler综合征患者采用FA作为标准成像方式,并使用激光光凝治疗视网膜非灌注区域.
