PDF(Pubmed)
Abstract：
Depression and anxiety often coexist with rheumatoid arthritis (RA) and affect the course of the disease. These mental health conditions can be overlooked or underdiagnosed in people with RA. There is conflicting evidence in previous studies regarding this topic, indicating that further research is necessary to provide a thorough understanding of the relationship between anxiety, depression, and RA. This study aims to determine the factors correlated with depression and anxiety symptoms in RA patients by evaluating disease activity at the same time. This cross-sectional study was conducted at four outpatient rehabilitation centers in four Syrian provinces: Damascus, Homs, Hama, and Latakia. The study included RA patients who attended the RA department of rehabilitation centers from January 1 to June 31, 2023. RA patients who presented at a rheumatology clinic were selected consecutively. RA patients were included in the study in accordance with the ACR/EULAR classification criteria, disease activity was assessed by disease activity score based on the 28-joint count (DAS28), and patients with DAS28 > 2.6 were considered to have active RA. The demographic data, as well as disease duration, educational status, Disease Activity Score with 28-joint counts (DAS28), health assessment questionnaire (HAQ) score, and the hospital anxiety and depression scale (HADS), were the parameters used in the analysis. Two hundred and twelve patients (female, 75%) with a mean age of 49.3 ± 13.1 years and a mean disease duration of 8.3 ± 6.9 years were studied. Depression was diagnosed in 79 (37.3%) patients and anxiety in 36 (16.9%) patients. Patients with depression and/or anxiety had higher HAQ and DAS28 scores compared to other RA patients. Blue-collar workers exhibited a higher prevalence of anxiety, whereas females, housewives, and individuals with lower educational attainment demonstrated a higher prevalence of depression. The current study found high rates of anxiety and depression in RA patients, highlighting the significant burden of these mental health conditions compared to the general population. It is essential for healthcare providers not to overlook the importance of psychiatric evaluations, mental health assessments, and physical examinations of RA patients.
摘要：
抑郁和焦虑常与类风湿关节炎（RA）并存，影响病程。这些精神健康状况在RA患者中可能被忽视或未被诊断。在以前的研究中有关于这个主题的相互矛盾的证据，这表明需要进一步的研究来提供对焦虑之间关系的透彻理解，抑郁症,RA。本研究旨在通过同时评估疾病活动来确定与RA患者抑郁和焦虑症状相关的因素。这项横断面研究是在叙利亚四个省的四个门诊康复中心进行的：大马士革，霍姆斯,Hama,还有拉塔基亚.该研究包括2023年1月1日至6月31日在康复中心RA部门就诊的RA患者。连续选择在风湿病诊所就诊的RA患者。根据ACR/EULAR分类标准将RA患者纳入研究，通过基于28关节计数（DAS28）的疾病活动性评分评估疾病活动性，DAS28>2.6的患者被认为是活动性RA。人口统计数据，以及疾病持续时间，教育状况,28关节计数的疾病活动评分（DAS28），健康评估问卷（HAQ）评分，和医院焦虑抑郁量表（HADS），是分析中使用的参数。二百一十二名患者(女，75％），平均年龄为49.3±13.1岁，平均疾病持续时间为8.3±6.9年。79例（37.3%）患者诊断为抑郁症，36例（16.9%）患者诊断为焦虑症。与其他RA患者相比，抑郁和/或焦虑患者的HAQ和DAS28评分更高。蓝领工人表现出更高的焦虑患病率，而女性，家庭主妇,受教育程度较低的个体表现出更高的抑郁症患病率。目前的研究发现RA患者焦虑和抑郁的发生率很高，强调与普通人群相比，这些精神健康状况的重大负担。对于医疗保健提供者来说，至关重要的是不要忽视精神病评估的重要性，心理健康评估,和RA患者的体格检查。
