Abstract：
Augustine is a newly identified blood group system comprising four antigens, one of which is the high-frequency antigen Ata in the original \"series\". Four antigens are located on a multipass membrane glycoprotein equilibrative nucleoside transporter 1 (ENT1), and equilibrative nucleoside transporter is encoded by SLC29A1. In 2016, the International Society of Blood Transfusion (ISBT) recognised Augustine as a blood group system and numbered it as 036. The glycoprotein ENT1 transports nucleotides into cells to participate in the synthesis of DNA and RNA, and this is an important link for chemotherapeutic glycosides to enter tumour cells. Augustine antibodies are clinically relevant in blood transfusion and pregnancy.
摘要：
奥古斯丁是一种新发现的包含四种抗原的血型系统，其中之一是原始“系列”中的高频抗原Ata。四个抗原位于多遍膜糖蛋白平衡核苷转运蛋白1（ENT1）上，和平衡核苷转运蛋白由SLC29A1编码。2016年，国际输血学会（ISBT）将奥古斯丁视为血型系统，并将其编号为036。糖蛋白ENT1将核苷酸转运到细胞中参与DNA和RNA的合成,这是化疗苷进入肿瘤细胞的重要环节。奥古斯丁抗体与输血和妊娠临床相关。
