新型肽类药物 ACTY116 原位成形植入物的制备及其对 SU5416 / 缺氧诱导的小鼠肺动脉高压和右心室肥厚的疗效评价
关键词: ACTY116 cardiac hypertrophy efficacy evaluation in situ forming implants pulmonary arterial hypertension
Mesh : Animals Hypertrophy, Right Ventricular / drug therapy Mice Disease Models, Animal Male Indoles / administration & dosage pharmacology Pyrroles / administration & dosage Hypoxia / drug therapy Pulmonary Arterial Hypertension / drug therapy Drug Implants Hypertension, Pulmonary / drug therapy etiology Oligopeptides / pharmacology administration & dosage Delayed-Action Preparations Polylactic Acid-Polyglycolic Acid Copolymer / chemistry Mice, Inbred C57BL Antihypertensive Agents / pharmacology administration & dosage