Abstract：
OBJECTIVE: Due to infectious complications of transrectal prostate biopsy (TRBx), the transperineal prostate biopsy (TPBx) technique is gaining popularity and is the first-line method in many institutions. We share our experience of the first 100 patients with TPBx, performed using the coaxial needle technique under local anesthesia.
METHODS: We retrospectively reviewed the records of the first 100 patients who had undergone TPBx between December 2022 and September 2023. Complication rates, cancer detection rates, patient tolerance, and pain response to the TPBx under local anesthesia at different steps of the procedure were collected.
RESULTS: The mean age, total prostate-specific antigen (PSA), prostate volume, and PSA density were 64.5±7.5 years, 8.82±12 ng/mL, 58.4±26.4 mL, and 0.17±0.18 ng/mL2. Prostate cancer (PCa) was detected at histopathological evaluation in 51 patients. The mean positive core number and percentage of cancer involvement per core in patients who have PCa were 5.4±3.2 and 68.5±29.1, respectively. The mean pain score during the entire procedure was 2.85±1.48. When the steps are evaluated separately, the mean pain score during the probe placement step, local anesthetic, and sampling steps were 3.35±1.65, 2.54±1.45, and 0.9±0.82, respectively.
CONCLUSIONS: Transperineal prostate biopsy with coaxial needle technique under local anesthesia is a well-tolerated procedure with feasible complication rates and patient discomfort.
METHODS: We retrospectively reviewed the records of the first 100 patients who had undergone TPBx between December 2022 and September 2023. Complication rates, cancer detection rates, patient tolerance, and pain response to the TPBx under local anesthesia at different steps of the procedure were collected.
RESULTS: The mean age, total prostate-specific antigen (PSA), prostate volume, and PSA density were 64.5±7.5 years, 8.82±12 ng/mL, 58.4±26.4 mL, and 0.17±0.18 ng/mL2. Prostate cancer (PCa) was detected at histopathological evaluation in 51 patients. The mean positive core number and percentage of cancer involvement per core in patients who have PCa were 5.4±3.2 and 68.5±29.1, respectively. The mean pain score during the entire procedure was 2.85±1.48. When the steps are evaluated separately, the mean pain score during the probe placement step, local anesthetic, and sampling steps were 3.35±1.65, 2.54±1.45, and 0.9±0.82, respectively.
CONCLUSIONS: Transperineal prostate biopsy with coaxial needle technique under local anesthesia is a well-tolerated procedure with feasible complication rates and patient discomfort.
摘要：
目的：由于经直肠前列腺活检（TRBx）的感染性并发症，经会阴前列腺活检(TPBx)技术越来越受欢迎,是许多机构的一线方法.我们分享了前100名TPBx患者的经验，在局部麻醉下使用同轴针技术进行。
方法：我们回顾性回顾了2022年12月至2023年9月接受TPBx治疗的前100例患者的记录。并发症发生率,癌症检出率，患者的耐受性，收集不同步骤的局部麻醉对TPBx的疼痛反应。
结果：平均年龄，总前列腺特异性抗原（PSA），前列腺体积,PSA密度为64.5±7.5年，8.82±12ng/mL，58.4±26.4mL，和0.17±0.18ng/mL2。51例患者在组织病理学评估中检测到前列腺癌（PCa）。PCa患者的平均阳性核心数和每个核心的癌症参与百分比分别为5.4±3.2和68.5±29.1。整个过程中的平均疼痛评分为2.85±1.48。当分别评估步骤时，探针放置步骤期间的平均疼痛评分，局部麻醉药,采样步长分别为3.35±1.65、2.54±1.45和0.9±0.82。
结论：局部麻醉下采用同轴针技术的经会阴前列腺活检是一种耐受性良好的手术，具有可行的并发症发生率和患者不适。
方法：我们回顾性回顾了2022年12月至2023年9月接受TPBx治疗的前100例患者的记录。并发症发生率,癌症检出率，患者的耐受性，收集不同步骤的局部麻醉对TPBx的疼痛反应。
结果：平均年龄，总前列腺特异性抗原（PSA），前列腺体积,PSA密度为64.5±7.5年，8.82±12ng/mL，58.4±26.4mL，和0.17±0.18ng/mL2。51例患者在组织病理学评估中检测到前列腺癌（PCa）。PCa患者的平均阳性核心数和每个核心的癌症参与百分比分别为5.4±3.2和68.5±29.1。整个过程中的平均疼痛评分为2.85±1.48。当分别评估步骤时，探针放置步骤期间的平均疼痛评分，局部麻醉药,采样步长分别为3.35±1.65、2.54±1.45和0.9±0.82。
结论：局部麻醉下采用同轴针技术的经会阴前列腺活检是一种耐受性良好的手术，具有可行的并发症发生率和患者不适。
