PDF(Pubmed)
Abstract：
UNASSIGNED: Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with Cytoreductive Surgery (CRS) is the preferred treatment for peritoneal malignancies. This highly complex operation is associated with a high incidence of complications, particularly due to malnutrition. This study aimed to investigate the potential association between preoperative nutritional status and postoperative clinical outcomes in adult cancer patients who underwent CRS/HIPEC for peritoneal malignancy.
UNASSIGNED: A retrospective study with 140 adult cancer patients, on parenteral nutrition (PN) (n = 40) and not on PN (n = 100) who underwent CRS with or without HIPEC, was conducted.
UNASSIGNED: Patients who received PN had significantly longer post-operative, hospital, and ICU LOS than those who did not (p = 0.001). ICU admission was significantly higher in the non-PN receiving group compared to the PN receiving group. When compared to the PN group, the majority of patients not receiving PN were at low risk of malnutrition (91% vs. 75%, p = 0.020), whereas 17.5% of PN patients were at risk of malnutrition during hospitalization. Multiple regression analyses revealed a strong positive relationship between patients with increased risk of malnutrition and ICU LOS (p = 0.047).
UNASSIGNED: Routine preoperative nutrition assessment is essential to identify patients who are at higher nutritional risk, and nutrition support should be provided preoperatively.
UNASSIGNED: A retrospective study with 140 adult cancer patients, on parenteral nutrition (PN) (n = 40) and not on PN (n = 100) who underwent CRS with or without HIPEC, was conducted.
UNASSIGNED: Patients who received PN had significantly longer post-operative, hospital, and ICU LOS than those who did not (p = 0.001). ICU admission was significantly higher in the non-PN receiving group compared to the PN receiving group. When compared to the PN group, the majority of patients not receiving PN were at low risk of malnutrition (91% vs. 75%, p = 0.020), whereas 17.5% of PN patients were at risk of malnutrition during hospitalization. Multiple regression analyses revealed a strong positive relationship between patients with increased risk of malnutrition and ICU LOS (p = 0.047).
UNASSIGNED: Routine preoperative nutrition assessment is essential to identify patients who are at higher nutritional risk, and nutrition support should be provided preoperatively.
摘要：
■腹膜热化疗（HIPEC）联合细胞减灭术（CRS）是腹膜恶性肿瘤的首选治疗方法。这种高度复杂的手术伴随着高发生率的并发症,特别是由于营养不良。本研究旨在探讨接受CRS/HIPEC治疗腹膜恶性肿瘤的成人癌症患者术前营养状况与术后临床结局之间的潜在关联。
■一项针对140名成年癌症患者的回顾性研究，肠外营养（PN）（n=40），而非PN（n=100），在有或没有HIPEC的情况下接受CRS，进行了。
■接受PN治疗的患者术后明显延长，医院,和ICULOS比那些没有（p=0.001）。非PN接受组的ICU入院率明显高于PN接受组。与PN组相比，大多数未接受PN的患者营养不良风险较低(91%vs.75%,p=0.020),而17.5%的PN患者在住院期间有营养不良的风险.多元回归分析显示，营养不良风险增加的患者与ICULOS之间存在很强的正相关关系（p=0.047）。
■常规术前营养评估对于识别营养风险较高的患者至关重要，术前应提供营养支持。
■一项针对140名成年癌症患者的回顾性研究，肠外营养（PN）（n=40），而非PN（n=100），在有或没有HIPEC的情况下接受CRS，进行了。
■接受PN治疗的患者术后明显延长，医院,和ICULOS比那些没有（p=0.001）。非PN接受组的ICU入院率明显高于PN接受组。与PN组相比，大多数未接受PN的患者营养不良风险较低(91%vs.75%,p=0.020),而17.5%的PN患者在住院期间有营养不良的风险.多元回归分析显示，营养不良风险增加的患者与ICULOS之间存在很强的正相关关系（p=0.047）。
■常规术前营养评估对于识别营养风险较高的患者至关重要，术前应提供营养支持。
