Abstract:
Platelet-rich plasma (PRP) is an autologous platelet concentrate in plasma enriched with growth factors that may stimulate tissue regeneration, collagen formation, re-epithelization, and angiogenesis. PRP is widely used as an androgenetic alopecia treatment option. The present work aims to test the efficacy of various PRP methods, including those with single-spin and double-spin centrifugation. We performed a review of articles published from 2011 to 2021 in PubMed and ScienceDirect. The studies vary in the preparation procedure, dose, number, intervals between the procedures, and the injection technique because of low standardization of PRP preparation, complicating the evaluation of the clinical efficacy of the method. Based on the conducted statistical analysis, we came to the conclusion that the double-spin PRP preparation method was superior to the single-spin technique, which may be taken into account for AGA management.
摘要:
富血小板血浆(PRP)是一种富含生长因子的自体血小板浓缩物,可刺激组织再生。胶原蛋白的形成,上皮再生,和血管生成。PRP被广泛用作雄激素性脱发治疗选择。本工作旨在测试各种PRP方法的有效性,包括单旋和双旋离心。我们对2011年至2021年在PubMed和ScienceDirect上发表的文章进行了审查。研究的准备程序各不相同,剂量,number,程序之间的间隔,和注射技术,因为PRP制备的标准化程度低,复杂的临床疗效评价方法。根据所进行的统计分析,我们得出的结论是,双自旋PRP制备方法优于单自旋技术,这可能会被考虑到AGA管理。